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7SFP
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BU of 7sfp by Molmil
Crystal structure of OssO, a spirocyclase involved in the biosynthesis of ossamycin
Descriptor: Spirocyclase
Authors:Bilyk, O, Leadlay, P.F, Dias, M.V.B.
Deposit date:2021-10-04
Release date:2022-08-17
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Enzyme-Catalyzed Spiroacetal Formation in Polyketide Antibiotic Biosynthesis.
J.Am.Chem.Soc., 144, 2022
7SFN
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BU of 7sfn by Molmil
Crystal structure of OlmO, a spirocyclase involved in the biosynthesis of oligomycin
Descriptor: D-MALATE, OlmO - oligomycin spirocyclase
Authors:Bilyk, O, Leadlay, P.F, Dias, M.V.B.
Deposit date:2021-10-04
Release date:2022-08-17
Last modified:2022-08-24
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Enzyme-Catalyzed Spiroacetal Formation in Polyketide Antibiotic Biosynthesis.
J.Am.Chem.Soc., 144, 2022
4U2I
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BU of 4u2i by Molmil
N-terminal domain of C. Rheinhardtii SAS-6 homolog bld12p Q93E G94D K146R Q147R (NN23)
Descriptor: Centriole protein
Authors:Hilbert, M, Kraatz, S.H.W.
Deposit date:2014-07-17
Release date:2015-07-29
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.281 Å)
Cite:SAS-6 engineering reveals interdependence between cartwheel and microtubules in determining centriole architecture.
Nat.Cell Biol., 18, 2016
6KYF
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BU of 6kyf by Molmil
Crystal structure of an anti-CRISPR protein
Descriptor: AcrF11, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Niu, Y, Wang, H, Zhang, Y, Feng, Y.
Deposit date:2019-09-18
Release date:2020-09-23
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (3.07 Å)
Cite:A Type I-F Anti-CRISPR Protein Inhibits the CRISPR-Cas Surveillance Complex by ADP-Ribosylation.
Mol.Cell, 80, 2020
4WBQ
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BU of 4wbq by Molmil
Crystal structure of the exonuclease domain of QIP (QDE-2 interacting protein) solved by native-SAD phasing.
Descriptor: CALCIUM ION, QDE-2-interacting protein
Authors:Boland, A, Weinert, T, Weichenrieder, O, Wang, M.
Deposit date:2014-09-03
Release date:2014-12-10
Last modified:2015-02-11
Method:X-RAY DIFFRACTION (2.693 Å)
Cite:Fast native-SAD phasing for routine macromolecular structure determination.
Nat.Methods, 12, 2015
4W99
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BU of 4w99 by Molmil
Apo-structure of the Y79F,W322E-double mutant of Etr1p
Descriptor: Enoyl-[acyl-carrier-protein] reductase [NADPH, B-specific] 1, mitochondrial, ...
Authors:Quade, N, Voegeli, B, Rosenthal, R, Erb, T.J.
Deposit date:2014-08-27
Release date:2015-03-18
Last modified:2015-05-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:The use of ene adducts to study and engineer enoyl-thioester reductases.
Nat.Chem.Biol., 11, 2015
6MH4
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BU of 6mh4 by Molmil
Crystal Structure of 1-deoxy-D-xylulose-5-phosphate reductoisomerase from Staphylococcus schleiferi, Apoenzyme
Descriptor: 1-deoxy-D-xylulose 5-phosphate reductoisomerase, SULFATE ION
Authors:Lee, S.G, Jez, J.M.
Deposit date:2018-09-17
Release date:2020-03-18
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Potent, specific MEPicides for treatment of zoonotic staphylococci.
Plos Pathog., 16, 2020
6MW5
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BU of 6mw5 by Molmil
UDP-galactose:glucoside-Skp1 alpha-D-galactosyltransferase with bound UDP and Platinum
Descriptor: 1,2-ETHANEDIOL, PLATINUM (II) ION, UDP-galactose:glucoside-Skp1 alpha-D-galactosyltransferase, ...
Authors:Kim, H.W, Wood, Z.A, West, C.M.
Deposit date:2018-10-29
Release date:2019-10-09
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A terminal alpha 3-galactose modification regulates an E3 ubiquitin ligase subunit in Toxoplasma gondii .
J.Biol.Chem., 295, 2020
6MH5
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BU of 6mh5 by Molmil
Crystal Structure of 1-deoxy-D-xylulose-5-phosphate reductoisomerase from Staphylococcus schleiferi in complex with Fosmidomycin (FOM)
Descriptor: 1-deoxy-D-xylulose 5-phosphate reductoisomerase, 3-[FORMYL(HYDROXY)AMINO]PROPYLPHOSPHONIC ACID
Authors:Lee, S.G, Jez, J.M.
Deposit date:2018-09-17
Release date:2020-03-18
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.887 Å)
Cite:Potent, specific MEPicides for treatment of zoonotic staphylococci.
Plos Pathog., 16, 2020
6MW8
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BU of 6mw8 by Molmil
UDP-galactose:glucoside-Skp1 alpha-D-galactosyltransferase with bound UDP and Manganese
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, MANGANESE (II) ION, ...
Authors:Kim, H.W, Wood, Z.A, West, C.M.
Deposit date:2018-10-29
Release date:2019-10-09
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.756 Å)
Cite:A terminal alpha 3-galactose modification regulates an E3 ubiquitin ligase subunit in Toxoplasma gondii .
J.Biol.Chem., 295, 2020
6MJV
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BU of 6mjv by Molmil
A consensus human beta defensin
Descriptor: Human beta-defensin
Authors:Amero, C, Villegas-Moreno, J, Rodriguez, A, Norton, R.S, Corzo, G.
Deposit date:2018-09-22
Release date:2019-08-28
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Antimicrobial activity and structure of a consensus human beta-defensin and its comparison to a novel putative hBD10.
Proteins, 88, 2020
5LCB
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BU of 5lcb by Molmil
In situ atomic-resolution structure of the baseplate antenna complex in Chlorobaculum tepidum obtained combining solid-state NMR spectroscopy, cryo electron microscopy and polarization spectroscopy
Descriptor: BACTERIOCHLOROPHYLL A, Bacteriochlorophyll c-binding protein
Authors:Nielsen, J.T, Kulminskaya, N.V, Bjerring, M, Linnanto, J.M, Ratsep, M, Pedersen, M, Lambrev, P.H, Dorogi, M, Garab, G, Thomsen, K, Jegerschold, C, Frigaard, N.U, Lindahl, M, Nielsen, N.C.
Deposit date:2016-06-20
Release date:2016-07-27
Last modified:2023-09-13
Method:ELECTRON MICROSCOPY (26.5 Å), SOLID-STATE NMR
Cite:In situ high-resolution structure of the baseplate antenna complex in Chlorobaculum tepidum.
Nat Commun, 7, 2016
8B7A
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BU of 8b7a by Molmil
Tubulin - maytansinoid - 4 complex
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Boiarska, Z, Perez-Pena, H, Abel, A.-C, Marzullo, P, Alvarez-Bernad, B, Bonato, F, Santini, B, Horvath, D, Lucena-Agell, D, Vasile, F, Sironi, M, Diaz, F.J, Steinmetz, M.O, Prota, A.E, Piaraccini, S, Passarella, D.
Deposit date:2022-09-29
Release date:2023-08-23
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Maytansinol Functionalization: Towards Useful Probes for Studying Microtubule Dynamics.
Chemistry, 29, 2023
8B7B
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BU of 8b7b by Molmil
Tubulin - maytansinoid - 6 complex
Descriptor: (~{Z})-11-[[(1~{R},2~{R},3~{S},5~{S},6~{S},16~{E},18~{E},20~{R},21~{S})-11-chloranyl-12,20-dimethoxy-2,5,9,16-tetramethyl-21-oxidanyl-8,23-bis(oxidanylidene)-4,24-dioxa-9,22-diazatetracyclo[19.3.1.1^{10,14}.0^{3,5}]hexacosa-10(26),11,13,16,18-pentaen-6-yl]oxy]-11-oxidanylidene-undec-2-enoic acid, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ...
Authors:Boiarska, Z, Perez-Pena, H, Abel, A.-C, Marzullo, P, Alvarez-Bernad, B, Bonato, F, Santini, B, Horvath, D, Lucena-Agell, D, Vasile, F, Sironi, M, Diaz, J.F, Steinmetz, M.O, Prota, A.E, Pieraccini, S, Passarella, D.
Deposit date:2022-09-29
Release date:2023-08-23
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Maytansinol Functionalization: Towards Useful Probes for Studying Microtubule Dynamics.
Chemistry, 29, 2023
8B7C
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BU of 8b7c by Molmil
Tubulin-maytansinoid-12 complex
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Boiarska, Z, Perez-Pena, H, Abel, A.-C, Marzullo, P, Alvarez-Bernad, B, Bonato, F, Santini, B, Horvath, D, Lucena-Agell, D, Vasile, F, Sironi, M, Diaz, J.F, Steinmetz, M.O, Prota, A.E, Pieraccini, S, Passarella, D.
Deposit date:2022-09-29
Release date:2023-08-23
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Maytansinol Functionalization: Towards Useful Probes for Studying Microtubule Dynamics.
Chemistry, 29, 2023
6O9N
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BU of 6o9n by Molmil
Structural insights on a new fungal aryl-alcohol oxidase
Descriptor: 1,2-ETHANEDIOL, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Kadowaki, M.A.S, Polikarpov, I.
Deposit date:2019-03-14
Release date:2020-03-18
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.598 Å)
Cite:Enzymatic versatility and thermostability of a new aryl-alcohol oxidase from Thermothelomyces thermophilus M77.
Biochim Biophys Acta Gen Subj, 1864, 2020
6P1F
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BU of 6p1f by Molmil
apo PmoF2 PCuAC domain
Descriptor: Copper chaperone PCu(A)C
Authors:Fisher, O.S, Sendzik, M.R, Rosenzweig, A.C.
Deposit date:2019-05-19
Release date:2019-09-25
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.654 Å)
Cite:PCuAC domains from methane-oxidizing bacteria use a histidine brace to bind copper.
J.Biol.Chem., 294, 2019
6PFY
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BU of 6pfy by Molmil
Membrane Protein Megahertz Crystallography at the European XFEL, Photosystem I at synchrotron to 2.9 A
Descriptor: 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, BETA-CAROTENE, ...
Authors:Fromme, R.
Deposit date:2019-06-23
Release date:2019-11-20
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Membrane protein megahertz crystallography at the European XFEL.
Nat Commun, 10, 2019
6P17
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BU of 6p17 by Molmil
Apo PCuAC domain from PmoF1
Descriptor: PmoF1
Authors:Sendzik, M.R, Fisher, O.S, Rosenzweig, A.C.
Deposit date:2019-05-19
Release date:2019-09-25
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.851 Å)
Cite:PCuAC domains from methane-oxidizing bacteria use a histidine brace to bind copper.
J.Biol.Chem., 294, 2019
1YGE
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BU of 1yge by Molmil
LIPOXYGENASE-1 (SOYBEAN) AT 100K
Descriptor: FE (III) ION, LIPOXYGENASE-1
Authors:Minor, W, Steczko, J, Stec, B, Otwinowski, Z, Bolin, J.T, Walter, R, Axelrod, B.
Deposit date:1996-06-04
Release date:1997-07-23
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Crystal structure of soybean lipoxygenase L-1 at 1.4 A resolution.
Biochemistry, 35, 1996
6P1E
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BU of 6p1e by Molmil
Cu-bound PmoF1 PCuAC domain (dimer)
Descriptor: COPPER (II) ION, PmoF1, THIOCYANATE ION
Authors:Fisher, O.S, Sendzik, M.R, Rosenzweig, A.C.
Deposit date:2019-05-19
Release date:2019-09-25
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.605 Å)
Cite:PCuAC domains from methane-oxidizing bacteria use a histidine brace to bind copper.
J.Biol.Chem., 294, 2019
6P16
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BU of 6p16 by Molmil
Cu-bound PCuAC domain from PmoF1
Descriptor: COPPER (II) ION, PmoF1
Authors:Sendzik, M.R, Fisher, O.S, Rosenzweig, A.C.
Deposit date:2019-05-19
Release date:2019-09-25
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.913 Å)
Cite:PCuAC domains from methane-oxidizing bacteria use a histidine brace to bind copper.
J.Biol.Chem., 294, 2019
6P1G
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BU of 6p1g by Molmil
Copper-bound PCuAC domain from PmoF2
Descriptor: COPPER (II) ION, Copper chaperone PCu(A)C, ZINC ION
Authors:Fisher, O.S, Rosenzweig, A.C.
Deposit date:2019-05-19
Release date:2019-09-25
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:PCuAC domains from methane-oxidizing bacteria use a histidine brace to bind copper.
J.Biol.Chem., 294, 2019
6PGK
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BU of 6pgk by Molmil
Membrane Protein Megahertz Crystallography at the European XFEL, Photosystem I XFEL at 2.9 A
Descriptor: 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, BETA-CAROTENE, ...
Authors:Fromme, R, Gisriel, C, Fromme, P.
Deposit date:2019-06-24
Release date:2019-11-27
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Membrane protein megahertz crystallography at the European XFEL.
Nat Commun, 10, 2019
4AGP
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BU of 4agp by Molmil
Structure of the p53 core domain mutant Y220C bound to the stabilizing small molecule PhiKan5176
Descriptor: 2-{[4-(diethylamino)piperidin-1-yl]methyl}-6-iodo-4-(3-phenoxyprop-1-yn-1-yl)phenol, CELLULAR TUMOR ANTIGEN P53, ZINC ION
Authors:Joerger, A.C, Wilcken, R, Fersht, A.R, Boeckler, F.M.
Deposit date:2012-01-30
Release date:2012-03-21
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Halogen-Enriched Fragment Libraries as Leads for Drug Rescue of Mutant P53.
J.Am.Chem.Soc., 134, 2012

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