3ORP
| Mycobacterium tuberculosis PknB kinase domain L33D mutant (crystal form 5) | Descriptor: | PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Serine/threonine protein kinase | Authors: | Good, M.C, Echols, N, Lombana, T.N, Alber, T, TB Structural Genomics Consortium (TBSGC) | Deposit date: | 2010-09-07 | Release date: | 2010-12-15 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Allosteric activation mechanism of the Mycobacterium tuberculosis receptor Ser/Thr kinase, PknB Structure, 18, 2010
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3OTV
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3ORO
| Mycobacterium tuberculosis PknB kinase domain L33D mutant (crystal form 4) | Descriptor: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Serine/threonine protein kinase | Authors: | Good, M.C, Echols, N, Lombana, T.N, Alber, T, TB Structural Genomics Consortium (TBSGC) | Deposit date: | 2010-09-07 | Release date: | 2010-12-15 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Allosteric activation mechanism of the Mycobacterium tuberculosis receptor Ser/Thr protein kinase, PknB. Structure, 18, 2010
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3OXH
| Mycobacterium tuberculosis kinase inhibitor homolog RV0577 | Descriptor: | CHLORIDE ION, PARA-MERCURY-BENZENESULFONIC ACID, RV0577 PROTEIN, ... | Authors: | Echols, N, Flynn, E.M, Stephenson, S, Ng, H.-L, Alber, T, TB Structural Genomics Consortium (TBSGC) | Deposit date: | 2010-09-21 | Release date: | 2011-10-19 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structural and Biophysical Characterization of the Mycobacterium tuberculosis Protein Rv0577, a Protein Associated with Neutral Red Staining of Virulent Tuberculosis Strains and Homologue of the Streptomyces coelicolor Protein KbpA. Biochemistry, 2017
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3ORM
| Mycobacterium tuberculosis PknB kinase domain D76A mutant | Descriptor: | MANGANESE (II) ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Serine/threonine protein kinase | Authors: | Echols, N, Lombana, T.N, Alber, T, TB Structural Genomics Consortium (TBSGC) | Deposit date: | 2010-09-07 | Release date: | 2010-12-15 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Allosteric activation mechanism of the Mycobacterium tuberculosis receptor Ser/Thr protein kinase, PknB. Structure, 18, 2010
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3ORT
| Mycobacterium tuberculosis PknB kinase domain L33D mutant (crystal form 6) | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Serine/threonine protein kinase | Authors: | Good, M.C, Echols, N, Lombana, T.N, Alber, T, TB Structural Genomics Consortium (TBSGC) | Deposit date: | 2010-09-07 | Release date: | 2010-12-15 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Allosteric activation mechanism of the Mycobacterium tuberculosis receptor Ser/Thr kinase, PknB Structure, 18, 2010
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3OUV
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3ORK
| Mycobacterium tuberculosis PknB kinase domain L33D mutant (crystal form 2) | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, MANGANESE (II) ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | Authors: | Echols, N, Lombana, T.N, Thomsen, N.D, Ng, H.-L, Alber, T, TB Structural Genomics Consortium (TBSGC) | Deposit date: | 2010-09-07 | Release date: | 2010-12-15 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Allosteric activation mechanism of the Mycobacterium tuberculosis receptor Ser/Thr kinase, PknB Structure, 18, 2010
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3RMR
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3TGP
| Room temperature H-ras | Descriptor: | GTPase HRas, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | Authors: | Fraser, J.S, Alber, T. | Deposit date: | 2011-08-17 | Release date: | 2011-10-12 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.3075 Å) | Cite: | Accessing protein conformational ensembles using room-temperature X-ray crystallography. Proc.Natl.Acad.Sci.USA, 108, 2011
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1QSC
| CRYSTAL STRUCTURE OF THE TRAF DOMAIN OF TRAF2 IN A COMPLEX WITH A PEPTIDE FROM THE CD40 RECEPTOR | Descriptor: | CD40 RECEPTOR, TNF RECEPTOR ASSOCIATED FACTOR 2 | Authors: | McWhirter, S.M, Pullen, S.S, Holton, J.M, Crute, J.J, Kehry, M.R, Alber, T. | Deposit date: | 1999-06-20 | Release date: | 1999-08-01 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystallographic analysis of CD40 recognition and signaling by human TRAF2. Proc.Natl.Acad.Sci.USA, 96, 1999
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1RWI
| Extracellular domain of Mycobacterium tuberculosis PknD | Descriptor: | CADMIUM ION, Serine/threonine-protein kinase pknD | Authors: | Good, M.C, Greenstein, A.E, Young, T.A, Ng, H.L, Alber, T, TB Structural Genomics Consortium (TBSGC) | Deposit date: | 2003-12-16 | Release date: | 2004-04-27 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Sensor Domain of the Mycobacterium tuberculosis Receptor Ser/Thr Protein Kinase, PknD, forms a Highly Symmetric beta Propeller. J.Mol.Biol., 339, 2004
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1RH4
| RH4 DESIGNED RIGHT-HANDED COILED COIL TETRAMER | Descriptor: | ISOPROPYL ALCOHOL, RIGHT-HANDED COILED COIL TETRAMER | Authors: | Harbury, P.B, Plecs, J.J, Tidor, B, Alber, T, Kim, P.S. | Deposit date: | 1998-10-07 | Release date: | 1998-12-02 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | High-resolution protein design with backbone freedom. Science, 282, 1998
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1RWL
| Extracellular domain of Mycobacterium tuberculosis PknD | Descriptor: | CADMIUM ION, Serine/threonine-protein kinase pknD | Authors: | Good, M.C, Greenstein, A.E, Young, T.A, Ng, H.L, Alber, T, TB Structural Genomics Consortium (TBSGC) | Deposit date: | 2003-12-16 | Release date: | 2004-04-27 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Sensor Domain of the Mycobacterium tuberculosis Receptor Ser/Thr Protein Kinase, PknD, forms a Highly Symmetric beta Propeller. J.Mol.Biol., 339, 2004
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1TXO
| Crystal structure of the Mycobacterium tuberculosis serine/threonine phosphatase PstP/Ppp at 1.95 A. | Descriptor: | MANGANESE (II) ION, Putative Bacterial Enzyme | Authors: | Pullen, K.E, Ng, H.L, Sung, P.Y, Good, M.C, Smith, S.M, Alber, T, TB Structural Genomics Consortium (TBSGC) | Deposit date: | 2004-07-05 | Release date: | 2004-11-23 | Last modified: | 2017-10-11 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | An Alternate Conformation and a Third Metal in PstP/Ppp, the M. tuberculosis PP2C-Family Ser/Thr Protein Phosphatase. Structure, 12, 2004
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1L10
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1L01
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1MRU
| Intracellular Ser/Thr protein kinase domain of Mycobacterium tuberculosis PknB. | Descriptor: | MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Probable serine/threonine-protein kinase pknB | Authors: | Young, T.A, Delagoutte, B, Endrizzi, J.A, Alber, T, TB Structural Genomics Consortium (TBSGC) | Deposit date: | 2002-09-18 | Release date: | 2003-02-11 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structure of Mycobacterium tuberculosis PknB supports a universal activation mechanism for Ser/Thr protein kinases. Nat.Struct.Biol., 10, 2003
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1L26
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1L30
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1L28
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1L32
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1L25
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1L31
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1L29
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