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6R4O
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BU of 6r4o by Molmil
Structure of a truncated adenylyl cyclase bound to MANT-GTP, forskolin and an activated stimulatory Galphas protein
Descriptor: 3'-O-(N-METHYLANTHRANILOYL)-GUANOSINE-5'-TRIPHOSPHATE, 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, Adenylate cyclase 9, ...
Authors:Qi, C, Sorrentino, S, Medalia, O, Korkhov, V.M.
Deposit date:2019-03-22
Release date:2019-05-08
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:The structure of a membrane adenylyl cyclase bound to an activated stimulatory G protein.
Science, 364, 2019
9EOH
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BU of 9eoh by Molmil
PHF type tau filament from in vitro V337M mutant
Descriptor: Isoform Tau-F of Microtubule-associated protein tau
Authors:Qi, C, Lovestam, S, Scheres, S.H.W, Michel, G.
Deposit date:2024-03-14
Release date:2024-05-29
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Tau filaments with the Alzheimer fold in cases with MAPT mutations V337M and R406W.
Biorxiv, 2024
9EOG
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BU of 9eog by Molmil
PHF type tau filament from R406W mutant
Descriptor: Microtubule-associated protein tau
Authors:Qi, C, Scheres, S.H.W, Michel, G.
Deposit date:2024-03-14
Release date:2024-05-29
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Tau filaments with the Alzheimer fold in cases with MAPT mutations V337M and R406W.
Biorxiv, 2024
7Z22
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BU of 7z22 by Molmil
Connexin43 gap junction channel structure in nanodisc
Descriptor: Gap junction alpha-1 protein
Authors:Qi, C, Korkhov, M.V.
Deposit date:2022-02-25
Release date:2023-03-08
Last modified:2023-08-16
Method:ELECTRON MICROSCOPY (2.95 Å)
Cite:Structure of the connexin-43 gap junction channel in a putative closed state.
Elife, 12, 2023
7Z23
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BU of 7z23 by Molmil
Connexin43 hemi channel in nanodisc
Descriptor: Gap junction alpha-1 protein
Authors:Qi, C, Korkhov, M.V.
Deposit date:2022-02-25
Release date:2023-03-08
Last modified:2023-08-16
Method:ELECTRON MICROSCOPY (3.98 Å)
Cite:Structure of the connexin-43 gap junction channel in a putative closed state.
Elife, 12, 2023
7Z1T
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BU of 7z1t by Molmil
Connexin43 gap junction channel structure in digitonin
Descriptor: Gap junction alpha-1 protein
Authors:Qi, C, Korkhov, M.V.
Deposit date:2022-02-25
Release date:2023-03-08
Last modified:2023-08-16
Method:ELECTRON MICROSCOPY (2.26 Å)
Cite:Structure of the connexin-43 gap junction channel in a putative closed state.
Elife, 12, 2023
9ERM
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BU of 9erm by Molmil
CTE type I tau filament from vacuolar tauopathy
Descriptor: Microtubule-associated protein tau
Authors:Qi, C, Scheres, H.W.S, Goedert, M.
Deposit date:2024-03-24
Release date:2024-05-29
Method:ELECTRON MICROSCOPY (2.3 Å)
Cite:Tau filaments with the chronic traumatic encephalopathy fold in a case of vacuolar tauopathy with VCP mutation D395G.
Acta Neuropathol, 147, 2024
9ERN
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BU of 9ern by Molmil
CTE type II tau filament from vacuolar tauopathy
Descriptor: Microtubule-associated protein tau
Authors:Qi, C, Scheres, H.W.S, Goedert, M.
Deposit date:2024-03-24
Release date:2024-05-29
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Tau filaments with the chronic traumatic encephalopathy fold in a case of vacuolar tauopathy with VCP mutation D395G.
Acta Neuropathol, 147, 2024
9ERO
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BU of 9ero by Molmil
CTE type II tau filament from vacuolar tauopathy
Descriptor: Microtubule-associated protein tau
Authors:Qi, C, Scheres, H.W.S, Goedert, M.
Deposit date:2024-03-24
Release date:2024-05-29
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Tau filaments with the chronic traumatic encephalopathy fold in a case of vacuolar tauopathy with VCP mutation D395G.
Acta Neuropathol, 147, 2024
7PD4
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BU of 7pd4 by Molmil
structure of Adenylyl cyclase 9 in complex with MANT-GTP
Descriptor: Adenylate cyclase 9
Authors:Qi, C, Korkhov, V.M.
Deposit date:2021-08-04
Release date:2022-01-19
Last modified:2022-03-09
Method:ELECTRON MICROSCOPY (4.9 Å)
Cite:Structural basis of adenylyl cyclase 9 activation.
Nat Commun, 13, 2022
7PDG
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BU of 7pdg by Molmil
structure of adenylyl cyclase 9 in complex with DARPin C4 and ATP-aS
Descriptor: Adenylate cyclase 9, DARPin C4
Authors:Qi, C, Korkhov, V.M.
Deposit date:2021-08-05
Release date:2022-01-19
Last modified:2022-03-09
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Structural basis of adenylyl cyclase 9 activation.
Nat Commun, 13, 2022
7PDH
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BU of 7pdh by Molmil
structure of adenylyl cyclase 9 in complex with DARPin C4 and ATP-aS
Descriptor: Adenylate cyclase 9, DARPin C4
Authors:Qi, C, Korkhov, V.M.
Deposit date:2021-08-05
Release date:2022-01-19
Last modified:2022-03-09
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structural basis of adenylyl cyclase 9 activation.
Nat Commun, 13, 2022
7PDE
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BU of 7pde by Molmil
Structure of Adenylyl cyclase 9 in complex with Gs protein alpha subunit and MANT-GTP
Descriptor: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, Adenylate cyclase 9, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ...
Authors:Qi, C, Korkhov, V.M.
Deposit date:2021-08-05
Release date:2022-01-19
Last modified:2022-03-09
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Structural basis of adenylyl cyclase 9 activation.
Nat Commun, 13, 2022
7PDF
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BU of 7pdf by Molmil
focus refinement of soluble domain of adenylyl cyclase 9 in complex with Gs protein alpha subunit and MANT-GTP
Descriptor: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, Adenylate cyclase 9, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ...
Authors:Qi, C, Korkhov, V.M.
Deposit date:2021-08-05
Release date:2022-01-26
Last modified:2022-03-09
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structural basis of adenylyl cyclase 9 activation.
Nat Commun, 13, 2022
7PDD
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BU of 7pdd by Molmil
Focus refinement of soluble domain of Adenylyl cyclase 9 in complex with DARPin C4 and MANT-GTP
Descriptor: Adenylate cyclase 9, DARPin C4
Authors:Qi, C, Korkhov, V.M.
Deposit date:2021-08-05
Release date:2022-01-19
Last modified:2022-03-09
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Structural basis of adenylyl cyclase 9 activation.
Nat Commun, 13, 2022
7PD8
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BU of 7pd8 by Molmil
Structure of Adenylyl cyclase 9 in complex with DARPin C4 and MANT-GTP
Descriptor: Adenylate cyclase 9, DARPin C4
Authors:Qi, C, Korkhov, V.M.
Deposit date:2021-08-04
Release date:2022-01-19
Last modified:2022-03-09
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Structural basis of adenylyl cyclase 9 activation.
Nat Commun, 13, 2022
8CAQ
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BU of 8caq by Molmil
Structure of Tau filaments Type I from Subacute Sclerosing Panencephalitis
Descriptor: Microtubule-associated protein tau
Authors:Qi, C, Hasegawa, M, Takao, M, Sakai, M, Akagi, M, Iwasaki, Y, Yoshida, M, Scheres, S.H.W, Goedert, M.
Deposit date:2023-01-24
Release date:2023-11-08
Method:ELECTRON MICROSCOPY (2.3 Å)
Cite:Identical tau filaments in subacute sclerosing panencephalitis and chronic traumatic encephalopathy.
Acta Neuropathol Commun, 11, 2023
8CAX
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BU of 8cax by Molmil
Structure of Tau filaments Type II from Subacute Sclerosing Panencephalitis
Descriptor: Microtubule-associated protein tau
Authors:Qi, C, Hasegawa, M, Takao, M, Sakai, M, Akagi, M, Iwasaki, Y, Yoshida, M, Scheres, S.H.W, Goedert, M.
Deposit date:2023-01-24
Release date:2023-11-08
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Identical tau filaments in subacute sclerosing panencephalitis and chronic traumatic encephalopathy.
Acta Neuropathol Commun, 11, 2023
7ZXQ
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BU of 7zxq by Molmil
cryo-EM structure of Connexin 32 R22G mutation hemi channel
Descriptor: Gap junction beta-1 protein
Authors:Qi, C, Korkhov, V.M.
Deposit date:2022-05-22
Release date:2023-05-31
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.53 Å)
Cite:Structures of wild-type and selected CMT1X mutant connexin 32 gap junction channels and hemichannels.
Sci Adv, 9, 2023
7ZXT
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BU of 7zxt by Molmil
cryo-EM structure of Connexin 32 W3S mutation hemi channel
Descriptor: Gap junction beta-1 protein
Authors:Qi, C, Korkhov, V.M.
Deposit date:2022-05-22
Release date:2023-05-31
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structures of wild-type and selected CMT1X mutant connexin 32 gap junction channels and hemichannels.
Sci Adv, 9, 2023
7ZXM
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BU of 7zxm by Molmil
cryo-EM structure of Connexin 32 gap junction channel
Descriptor: Gap junction beta-1 protein
Authors:Qi, C, Korkhov, V.M.
Deposit date:2022-05-21
Release date:2023-05-31
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (2.14 Å)
Cite:Structures of wild-type and selected CMT1X mutant connexin 32 gap junction channels and hemichannels.
Sci Adv, 9, 2023
7ZXP
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BU of 7zxp by Molmil
cryo-EM structure of Connexin 32 R22G mutation gap junction channel
Descriptor: Gap junction beta-1 protein
Authors:Qi, C, Korkhov, V.M.
Deposit date:2022-05-22
Release date:2023-05-31
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (2.39 Å)
Cite:Structures of wild-type and selected CMT1X mutant connexin 32 gap junction channels and hemichannels.
Sci Adv, 9, 2023
7ZXN
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BU of 7zxn by Molmil
cryo-EM structure of Connexin 32 gap junction channel
Descriptor: CHOLESTEROL, Gap junction beta-1 protein
Authors:Qi, C, Korkhov, V.M.
Deposit date:2022-05-21
Release date:2023-05-31
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.06 Å)
Cite:Structures of wild-type and selected CMT1X mutant connexin 32 gap junction channels and hemichannels.
Sci Adv, 9, 2023
7ZXO
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BU of 7zxo by Molmil
cryo-EM structure of Connexin 32 gap junction channel
Descriptor: Gap junction beta-1 protein
Authors:Qi, C, Korkhov, V.M.
Deposit date:2022-05-21
Release date:2023-05-31
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Structures of wild-type and selected CMT1X mutant connexin 32 gap junction channels and hemichannels.
Sci Adv, 9, 2023
8OTD
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BU of 8otd by Molmil
TMEM106B Fold1-s filament from Guam ALS/PDC
Descriptor: Transmembrane protein 106B
Authors:Qi, C, Yang, S, Scheres, S.H.W, Goedert, M.
Deposit date:2023-04-20
Release date:2024-03-27
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Tau filaments from amyotrophic lateral sclerosis/parkinsonism-dementia complex adopt the CTE fold.
Proc.Natl.Acad.Sci.USA, 120, 2023

 

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