8JCV
 
 | | Cryo-EM structure of mGlu2-mGlu3 heterodimer in presence of LY341495 (dimerization mode II) | | Descriptor: | 2-[(1S,2S)-2-carboxycyclopropyl]-3-(9H-xanthen-9-yl)-D-alanine, 2-acetamido-2-deoxy-beta-D-glucopyranose, Metabotropic glutamate receptor 2,Peptidyl-prolyl cis-trans isomerase FKBP1A, ... | | Authors: | Wang, X, Wang, M, Xu, T, Feng, Y, Han, S, Zhao, Q, Wu, B. | | Deposit date: | 2023-05-12 | | Release date: | 2023-06-21 | | Last modified: | 2023-10-18 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Structural insights into dimerization and activation of the mGlu2-mGlu3 and mGlu2-mGlu4 heterodimers.
Cell Res., 33, 2023
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8JD2
 | | Cryo-EM structure of G protein-free mGlu2-mGlu3 heterodimer in Acc state | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GLUTAMIC ACID, Metabotropic glutamate receptor 2,Peptidyl-prolyl cis-trans isomerase FKBP1A, ... | | Authors: | Wang, X, Wang, M, Xu, T, Feng, Y, Han, S, Lin, S, Zhao, Q, Wu, B. | | Deposit date: | 2023-05-12 | | Release date: | 2023-06-21 | | Last modified: | 2023-10-18 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Structural insights into dimerization and activation of the mGlu2-mGlu3 and mGlu2-mGlu4 heterodimers.
Cell Res., 33, 2023
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8JD5
 | | Cryo-EM structure of Gi1-bound mGlu2-mGlu4 heterodimer | | Descriptor: | 1-butyl-3-chloranyl-4-(4-phenylpiperidin-1-yl)pyridin-2-one, 2-acetamido-2-deoxy-beta-D-glucopyranose, 5-methyl-N-(4-methylpyrimidin-2-yl)-4-(1H-pyrazol-4-yl)-1,3-thiazol-2-amine, ... | | Authors: | Wang, X, Wang, M, Xu, T, Feng, Y, Han, S, Zhao, Q, Wu, B. | | Deposit date: | 2023-05-12 | | Release date: | 2023-06-21 | | Last modified: | 2023-10-18 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Structural insights into dimerization and activation of the mGlu2-mGlu3 and mGlu2-mGlu4 heterodimers.
Cell Res., 33, 2023
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8JCU
 | | Cryo-EM structure of mGlu2-mGlu3 heterodimer in presence of LY341495 (dimerization mode I) | | Descriptor: | 2-[(1S,2S)-2-carboxycyclopropyl]-3-(9H-xanthen-9-yl)-D-alanine, 2-acetamido-2-deoxy-beta-D-glucopyranose, Metabotropic glutamate receptor 2,Peptidyl-prolyl cis-trans isomerase FKBP1A, ... | | Authors: | Wang, X, Wang, M, Xu, T, Feng, Y, Zhao, Q, Wu, B. | | Deposit date: | 2023-05-12 | | Release date: | 2023-06-21 | | Last modified: | 2023-10-18 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Structural insights into dimerization and activation of the mGlu2-mGlu3 and mGlu2-mGlu4 heterodimers.
Cell Res., 33, 2023
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8JD3
 | | Cryo-EM structure of Gi1-bound mGlu2-mGlu3 heterodimer | | Descriptor: | 1-butyl-3-chloranyl-4-(4-phenylpiperidin-1-yl)pyridin-2-one, CHOLESTEROL, DI-PALMITOYL-3-SN-PHOSPHATIDYLETHANOLAMINE, ... | | Authors: | Wang, X, Wang, M, Xu, T, Feng, Y, Han, S, Lin, S, Zhao, Q, Wu, B. | | Deposit date: | 2023-05-12 | | Release date: | 2023-06-21 | | Last modified: | 2023-10-18 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Structural insights into dimerization and activation of the mGlu2-mGlu3 and mGlu2-mGlu4 heterodimers.
Cell Res., 33, 2023
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8JD1
 | | Cryo-EM structure of mGlu2-mGlu3 heterodimer in Rco state | | Descriptor: | CHOLESTEROL, GLUTAMIC ACID, Metabotropic glutamate receptor 2,Peptidyl-prolyl cis-trans isomerase FKBP1A, ... | | Authors: | Wang, X, Wang, M, Xu, T, Feng, Y, Han, S, Lin, S, Zhao, Q, Wu, B. | | Deposit date: | 2023-05-12 | | Release date: | 2023-06-21 | | Last modified: | 2023-10-18 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Structural insights into dimerization and activation of the mGlu2-mGlu3 and mGlu2-mGlu4 heterodimers.
Cell Res., 33, 2023
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8JCW
 | | Cryo-EM structure of mGlu2-mGlu3 heterodimer in presence of LY341495 and NAM563 (dimerization mode I) | | Descriptor: | 2-[(1S,2S)-2-carboxycyclopropyl]-3-(9H-xanthen-9-yl)-D-alanine, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, ... | | Authors: | Wang, X, Wang, M, Xu, T, Feng, Y, Han, S, Lin, S, Zhao, Q, Wu, B. | | Deposit date: | 2023-05-12 | | Release date: | 2023-06-21 | | Last modified: | 2023-10-18 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Structural insights into dimerization and activation of the mGlu2-mGlu3 and mGlu2-mGlu4 heterodimers.
Cell Res., 33, 2023
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8JD4
 | | Cryo-EM structure of G protein-free mGlu2-mGlu4 heterodimer in Acc state | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GLUTAMIC ACID, Metabotropic glutamate receptor 2,Peptidyl-prolyl cis-trans isomerase FKBP1A, ... | | Authors: | Wang, X, Wang, M, Xu, T, Feng, Y, Han, S, Lin, S, Zhao, Q, Wu, B. | | Deposit date: | 2023-05-12 | | Release date: | 2023-06-21 | | Last modified: | 2023-10-18 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Structural insights into dimerization and activation of the mGlu2-mGlu3 and mGlu2-mGlu4 heterodimers.
Cell Res., 33, 2023
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8JCY
 | | Cryo-EM structure of mGlu2-mGlu3 heterodimer in presence of LY341495, NAM563, and LY2389575 (dimerization mode I) | | Descriptor: | 2-[(1S,2S)-2-carboxycyclopropyl]-3-(9H-xanthen-9-yl)-D-alanine, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, ... | | Authors: | Wang, X, Wang, M, Xu, T, Feng, Y, Han, S, Lin, S, Zhao, Q, Wu, B. | | Deposit date: | 2023-05-12 | | Release date: | 2023-06-21 | | Last modified: | 2023-10-18 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Structural insights into dimerization and activation of the mGlu2-mGlu3 and mGlu2-mGlu4 heterodimers.
Cell Res., 33, 2023
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8JCZ
 | | Cryo-EM structure of mGlu2-mGlu3 heterodimer in presence of LY341495, NAM563, and LY2389575 (dimerization mode III) | | Descriptor: | 2-[(1S,2S)-2-carboxycyclopropyl]-3-(9H-xanthen-9-yl)-D-alanine, 2-acetamido-2-deoxy-beta-D-glucopyranose, Metabotropic glutamate receptor 2,Peptidyl-prolyl cis-trans isomerase FKBP1A, ... | | Authors: | Wang, X, Wang, M, Xu, T, Feng, Y, Han, S, Lin, S, Zhao, Q, Wu, B. | | Deposit date: | 2023-05-12 | | Release date: | 2023-06-21 | | Last modified: | 2023-10-18 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Structural insights into dimerization and activation of the mGlu2-mGlu3 and mGlu2-mGlu4 heterodimers.
Cell Res., 33, 2023
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8JCX
 | | Cryo-EM structure of mGlu2-mGlu3 heterodimer in presence of LY341495 and NAM563 (dimerization mode II) | | Descriptor: | 2-[(1S,2S)-2-carboxycyclopropyl]-3-(9H-xanthen-9-yl)-D-alanine, 2-acetamido-2-deoxy-beta-D-glucopyranose, Metabotropic glutamate receptor 2,Peptidyl-prolyl cis-trans isomerase FKBP1A, ... | | Authors: | Wang, X, Wang, M, Xu, T, Feng, Y, Han, S, Lin, S, Zhao, Q, Wu, B. | | Deposit date: | 2023-05-12 | | Release date: | 2023-06-21 | | Last modified: | 2023-10-18 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Structural insights into dimerization and activation of the mGlu2-mGlu3 and mGlu2-mGlu4 heterodimers.
Cell Res., 33, 2023
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8JD0
 | | Cryo-EM structure of mGlu2-mGlu3 heterodimer in presence of NAM563 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(1-methylpyrazol-4-yl)-7-[[(2~{S})-2-(trifluoromethyl)morpholin-4-yl]methyl]quinoline-2-carboxamide, CHOLESTEROL, ... | | Authors: | Wang, X, Wang, M, Xu, T, Feng, Y, Han, S, Lin, S, Zhao, Q, Wu, B. | | Deposit date: | 2023-05-12 | | Release date: | 2023-06-21 | | Last modified: | 2023-10-18 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Structural insights into dimerization and activation of the mGlu2-mGlu3 and mGlu2-mGlu4 heterodimers.
Cell Res., 33, 2023
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5X6O
 | | Intact ATR/Mec1-ATRIP/Ddc2 complex | | Descriptor: | DNA damage checkpoint protein LCD1, Serine/threonine-protein kinase MEC1 | | Authors: | Wang, X, Ran, T, Cai, G. | | Deposit date: | 2017-02-22 | | Release date: | 2017-12-20 | | Last modified: | 2019-11-06 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | 3.9 angstrom structure of the yeast Mec1-Ddc2 complex, a homolog of human ATR-ATRIP.
Science, 358, 2017
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2L9H
 | | Oligomeric Structure of the Chemokine CCL5/RANTES from NMR, MS, and SAXS Data | | Descriptor: | C-C motif chemokine 5 | | Authors: | Wang, X, Watson, C.M, Sharp, J.S, Handel, T.M, Prestegard, J.H. | | Deposit date: | 2011-02-09 | | Release date: | 2011-06-22 | | Last modified: | 2011-08-24 | | Method: | SOLUTION NMR, SOLUTION SCATTERING | | Cite: | Oligomeric Structure of the Chemokine CCL5/RANTES from NMR, MS, and SAXS Data.
Structure, 19, 2011
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6AJ8
 | | Crystal structure of Trypanosoma brucei glycosomal isocitrate dehydrogenase in complex with NADP+, alpha-ketoglutarate and ca2+ | | Descriptor: | 2-OXOGLUTARIC ACID, CALCIUM ION, Isocitrate dehydrogenase [NADP], ... | | Authors: | Wang, X, Inaoka, D.K, Shiba, T, Balogun, E.O, Ziebart, N, Allman, S, Watanabe, Y, Nozaki, T, Boshart, M, Bringaud, F, Harada, S, Kita, K. | | Deposit date: | 2018-08-27 | | Release date: | 2019-08-28 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Biochemical characterization of a novel Trypanosoma brucei glycosomal isocitrate dehydrogenase with dual coenzyme specificity (NADP+/NAD+)
To Be Published
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5DQR
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5HLZ
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5HLY
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6NIF
 | | crystal structure of human REV7-RAN complex | | Descriptor: | hREV7, GTP-binding nuclear protein Ran, hREV3 fusion | | Authors: | Wang, X, Pertz, L, Hua, D.P, Zhang, T.Q, Listovsky, T, Xie, W. | | Deposit date: | 2018-12-27 | | Release date: | 2019-09-11 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.002 Å) | | Cite: | REV7 has a dynamic adaptor region to accommodate small GTPase RAN/ShigellaIpaB ligands, and its activity is regulated by the RanGTP/GDP switch.
J.Biol.Chem., 294, 2019
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4JDZ
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4JE0
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2JT8
 | | Solution structure of the F153-to-5-flurotryptophan mutant of human cardiac troponin C | | Descriptor: | Troponin C, slow skeletal and cardiac muscles | | Authors: | Wang, X, Mercier, P, Letourneau, P, Sykes, B.D. | | Deposit date: | 2007-07-20 | | Release date: | 2007-08-07 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | Effects of Phe-to-Trp mutation and fluorotryptophan incorporation on the solution structure of cardiac troponin C, and analysis of its suitability as a potential probe for in situ NMR studies
Protein Sci., 14, 2005
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2JT3
 | | Solution Structure of F153W cardiac troponin C | | Descriptor: | Troponin C | | Authors: | Wang, X, Mercier, P, Letourneau, P, Sykes, B.D. | | Deposit date: | 2007-07-18 | | Release date: | 2007-07-31 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Effects of Phe-to-Trp mutation and fluorotryptophan incorporation on the solution structure of cardiac troponin C, and analysis of its suitability as a potential probe for in situ NMR studies.
Protein Sci., 14, 2005
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2JTZ
 | | Solution structure and chemical shift assignments of the F104-to-5-flurotryptophan mutant of cardiac troponin C | | Descriptor: | Troponin C, slow skeletal and cardiac muscles | | Authors: | Wang, X, Mercier, P, Letourneau, P, Sykes, B.D. | | Deposit date: | 2007-08-10 | | Release date: | 2007-08-28 | | Last modified: | 2021-10-20 | | Method: | SOLUTION NMR | | Cite: | Effects of Phe-to-Trp mutation and fluorotryptophan incorporation on the solution structure of cardiac troponin C, and analysis of its suitability as a potential probe for in situ NMR studies
Protein Sci., 14, 2005
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2K2R
 | | The NMR structure of alpha-parvin CH2/paxillin LD1 complex | | Descriptor: | Alpha-parvin, Paxillin | | Authors: | Wang, X, Fukuda, K, Byeon, I, Velyvis, A, Wu, C, Gronenborn, A, Qin, J. | | Deposit date: | 2008-04-10 | | Release date: | 2008-05-27 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | The Structure of {alpha}-Parvin CH2-Paxillin LD1 Complex Reveals a Novel Modular Recognition for Focal Adhesion Assembly.
J.Biol.Chem., 283, 2008
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