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2XNV
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BU of 2xnv by Molmil
Acetylcholine binding protein (AChBP) as template for hierarchical in silico screening procedures to identify structurally novel ligands for the nicotinic receptors
Descriptor: 2-(2-(4-PHENYLPIPERIDIN-1-YL)ETHYL)-1H-INDOLE, SOLUBLE ACETYLCHOLINE RECEPTOR
Authors:Rucktooa, P, Akdemir, A, deEsch, I, Sixma, T.K.
Deposit date:2010-08-06
Release date:2011-08-24
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.44 Å)
Cite:Acetylcholine Binding Protein (Achbp) as Template for Hierarchical in Silico Screening Procedures to Identify Structurally Novel Ligands for the Nicotinic Receptors.
Bioorg.Med.Chem., 19, 2011
2Y4W
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BU of 2y4w by Molmil
Solution structure of human ubiquitin conjugating enzyme Rad6b
Descriptor: UBIQUITIN-CONJUGATING ENZYME E2 B
Authors:Huang, A, Hibbert, R.G, deJong, R.N, Das, D, Sixma, T.K, Boelens, R.
Deposit date:2011-01-11
Release date:2011-05-11
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Symmetry and Asymmetry of the Ring-Ring Dimer of Rad18
J.Mol.Biol., 410, 2011
5L8W
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BU of 5l8w by Molmil
Structure of USP12-UB-PRG/UAF1
Descriptor: GLYCEROL, Polyubiquitin-B, Ubiquitin carboxyl-terminal hydrolase 12, ...
Authors:Dharadhar, S, Sixma, T.
Deposit date:2016-06-08
Release date:2016-09-28
Last modified:2016-11-30
Method:X-RAY DIFFRACTION (2.79 Å)
Cite:A conserved two-step binding for the UAF1 regulator to the USP12 deubiquitinating enzyme.
J.Struct.Biol., 196, 2016
5L8H
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BU of 5l8h by Molmil
Structure of USP46-UbVME
Descriptor: Polyubiquitin-B, Ubiquitin carboxyl-terminal hydrolase 46, ZINC ION
Authors:Clerici, M, Sixma, T, Dharadhar, S.
Deposit date:2016-06-07
Release date:2016-09-28
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:A conserved two-step binding for the UAF1 regulator to the USP12 deubiquitinating enzyme.
J.Struct.Biol., 196, 2016
5L8E
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BU of 5l8e by Molmil
Structure of UAF1
Descriptor: GLYCEROL, Unknown, WD repeat-containing protein 48
Authors:Dharadhar, S, Sixma, T.
Deposit date:2016-06-07
Release date:2016-09-28
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:A conserved two-step binding for the UAF1 regulator to the USP12 deubiquitinating enzyme.
J.Struct.Biol., 196, 2016
1HC9
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alpha-bungarotoxin complexed with high affinity peptide
Descriptor: ALPHA-BUNGAROTOXIN ISOFORM A31, ALPHA-BUNGAROTOXIN ISOFORM V31, IODIDE ION, ...
Authors:Harel, M, Kasher, R, Sussman, J.L.
Deposit date:2001-05-02
Release date:2001-11-10
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The Binding Site of Acetylcholine Receptor as Visualized in the X-Ray Structure of a Complex between Alpha-Bungarotoxin and a Mimotope Peptide.
Neuron, 32, 2001
6AQR
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BU of 6aqr by Molmil
SAGA DUB module Ubp8(C146A)/Sgf11/Sus1/Sgf73 bound to monoubiquitin
Descriptor: Polyubiquitin-C, SAGA-associated factor 11, SAGA-associated factor 73, ...
Authors:Morrow, M.E, Morgan, M.T, Wolberger, C.
Deposit date:2017-08-21
Release date:2018-07-04
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Active site alanine mutations convert deubiquitinases into high-affinity ubiquitin-binding proteins.
EMBO Rep., 19, 2018
6QLZ
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BU of 6qlz by Molmil
IDOL F3ab subdomain
Descriptor: E3 ubiquitin-protein ligase MYLIP
Authors:Martinelli, L, Johansson, P, Wan, P.T, Gunnarsson, J, Guo, H, Boyd, H.
Deposit date:2019-02-01
Release date:2020-02-19
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.343 Å)
Cite:Structural analysis of the LDL receptor-interacting FERM domain in the E3 ubiquitin ligase IDOL reveals an obscured substrate-binding site.
J.Biol.Chem., 295, 2020
1EMB
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BU of 1emb by Molmil
GREEN FLUORESCENT PROTEIN (GFP) FROM AEQUOREA VICTORIA, GLN 80 REPLACED WITH ARG
Descriptor: GREEN FLUORESCENT PROTEIN
Authors:Brejc, K, Sixma, T.
Deposit date:1997-01-08
Release date:1997-06-16
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.13 Å)
Cite:Structural basis for dual excitation and photoisomerization of the Aequorea victoria green fluorescent protein.
Proc.Natl.Acad.Sci.USA, 94, 1997
1EFI
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BU of 1efi by Molmil
HEAT-LABILE ENTEROTOXIN B-PENTAMER COMPLEXED WITH PARA-AMINOPHENYL-ALPHA-D-GALACTOPYRANOSIDE
Descriptor: 4-aminophenyl alpha-D-galactopyranoside, PROTEIN (HEAT-LABILE ENTEROTOXIN B CHAIN)
Authors:Merritt, E.A, Hol, W.G.J.
Deposit date:2000-02-08
Release date:2000-02-23
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Exploration of the GM1 receptor-binding site of heat-labile enterotoxin and cholera toxin by phenyl-ring-containing galactose derivatives.
Acta Crystallogr.,Sect.D, 57, 2001
2MOA
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BU of 2moa by Molmil
Solution NMR structure of peptide ImI1 (peak 2)
Descriptor: Alpha-conotoxin ImI
Authors:Heinis, C, Chen, S.
Deposit date:2014-04-24
Release date:2014-09-24
Last modified:2023-11-15
Method:SOLUTION NMR
Cite:Dithiol amino acids can structurally shape and enhance the ligand-binding properties of polypeptides.
Nat Chem, 6, 2014
1HTL
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BU of 1htl by Molmil
MUTATION OF A BURIED RESIDUE CAUSES LACK OF ACTIVITY BUT NO CONFORMATIONAL CHANGE: CRYSTAL STRUCTURE OF E. COLI HEAT-LABILE ENTEROTOXIN MUTANT VAL 97--> LYS
Descriptor: HEAT-LABILE ENTEROTOXIN, SUBUNIT A, SUBUNIT B
Authors:Merritt, E.A, Hol, W.G.J.
Deposit date:1995-02-15
Release date:1995-04-20
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Mutation of a buried residue causes loss of activity but no conformational change in the heat-labile enterotoxin of Escherichia coli.
Nat.Struct.Biol., 2, 1995
1LT5
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BU of 1lt5 by Molmil
HEAT-LABILE ENTEROTOXIN B-PENTAMER COMPLEXED WITH THIODIGALACTOSIDE
Descriptor: HEAT-LABILE ENTEROTOXIN, beta-D-galactopyranose-(1-1)-1-thio-beta-D-galactopyranose
Authors:Merritt, E.A, Hol, W.G.J.
Deposit date:1997-09-30
Release date:1997-12-03
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural foundation for the design of receptor antagonists targeting Escherichia coli heat-labile enterotoxin.
Structure, 5, 1997
1LT3
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BU of 1lt3 by Molmil
HEAT-LABILE ENTEROTOXIN DOUBLE MUTANT N40C/G166C
Descriptor: HEAT-LABILE ENTEROTOXIN, beta-D-galactopyranose-(1-4)-beta-D-glucopyranose
Authors:Van Den Akker, F, Hol, W.G.J.
Deposit date:1997-04-12
Release date:1997-07-07
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of heat-labile enterotoxin from Escherichia coli with increased thermostability introduced by an engineered disulfide bond in the A subunit.
Protein Sci., 6, 1997
1LT4
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BU of 1lt4 by Molmil
HEAT-LABILE ENTEROTOXIN MUTANT S63K
Descriptor: HEAT-LABILE ENTEROTOXIN, beta-D-galactopyranose-(1-4)-beta-D-glucopyranose
Authors:Van Den Akker, F, Hol, W.G.J.
Deposit date:1997-04-14
Release date:1997-06-16
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of a non-toxic mutant of heat-labile enterotoxin, which is a potent mucosal adjuvant.
Protein Sci., 6, 1997
1LT6
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BU of 1lt6 by Molmil
HEAT-LABILE ENTEROTOXIN B-PENTAMER COMPLEXED WITH METANITROPHENYLGALACTOSIDE
Descriptor: 3-nitrophenyl alpha-D-galactopyranoside, HEAT-LABILE ENTEROTOXIN
Authors:Merritt, E.A, Hol, W.G.J.
Deposit date:1997-10-01
Release date:1997-12-03
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural foundation for the design of receptor antagonists targeting Escherichia coli heat-labile enterotoxin.
Structure, 5, 1997
1LTG
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BU of 1ltg by Molmil
THE ARG7LYS MUTANT OF HEAT-LABILE ENTEROTOXIN EXHIBITS GREAT FLEXIBILITY OF ACTIVE SITE LOOP 47-56 OF THE A SUBUNIT
Descriptor: HEAT-LABILE ENTEROTOXIN
Authors:Van Den Akker, F, Hol, W.G.J.
Deposit date:1995-06-13
Release date:1995-09-15
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The Arg7Lys mutant of heat-labile enterotoxin exhibits great flexibility of active site loop 47-56 of the A subunit.
Biochemistry, 34, 1995
1B44
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BU of 1b44 by Molmil
CRYSTAL STRUCTURE OF THE B SUBUNIT OF HEAT-LABILE ENTEROTOXIN FROM E. COLI CARRYING A PEPTIDE WITH ANTI-HSV ACTIVITY
Descriptor: PROTEIN (B-POL SUBUNIT OF HEAT-LABILE ENTEROTOXIN)
Authors:Matkovic-Calogovic, D, Loregian, A, D'Acunto, M.R, Battistutta, R, Tossi, A, Palu, G, Zanotti, G.
Deposit date:1999-01-04
Release date:1999-01-13
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Crystal structure of the B subunit of Escherichia coli heat-labile enterotoxin carrying peptides with anti-herpes simplex virus type 1 activity.
J.Biol.Chem., 274, 1999
1TII
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BU of 1tii by Molmil
ESCHERICHIA COLI HEAT LABILE ENTEROTOXIN TYPE IIB
Descriptor: HEAT LABILE ENTEROTOXIN TYPE IIB
Authors:Van Den Akker, F, Hol, W.G.J.
Deposit date:1996-03-20
Release date:1996-08-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Crystal structure of a new heat-labile enterotoxin, LT-IIb.
Structure, 4, 1996
1LTR
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BU of 1ltr by Molmil
CRYSTAL STRUCTURE OF THE B SUBUNIT OF HUMAN HEAT-LABILE ENTEROTOXIN FROM E. COLI CARRYING A PEPTIDE WITH ANTI-HSV ACTIVITY
Descriptor: HEAT-LABILE ENTEROTOXIN, SULFATE ION
Authors:Matkovic-Calogovic, D, Loreggian, A, Palu, G, Zanotti, G.
Deposit date:1998-07-31
Release date:1999-02-09
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (3.04 Å)
Cite:Crystal structure of the B subunit of Escherichia coli heat-labile enterotoxin carrying peptides with anti-herpes simplex virus type 1 activity.
J.Biol.Chem., 274, 1999
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