6EWH
 
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6EWL
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5LPI
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5LNP
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5LPH
 | | Structure of the TOG domain of human Cep104 | | Descriptor: | Centrosomal protein of 104 kDa | | Authors: | van Breugel, M. | | Deposit date: | 2016-08-13 | | Release date: | 2017-01-11 | | Last modified: | 2017-09-13 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | The Ciliopathy-Associated Cep104 Protein Interacts with Tubulin and Nek1 Kinase.
Structure, 25, 2017
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5OID
 | | Complex Trichoplax STIL-NTD:human CEP85 coiled coil domain 4 | | Descriptor: | Centrosomal protein of 85 kDa, Putative uncharacterized protein | | Authors: | van Breugel, M. | | Deposit date: | 2017-07-18 | | Release date: | 2018-04-18 | | Last modified: | 2018-05-09 | | Method: | X-RAY DIFFRACTION (4.6 Å) | | Cite: | Direct binding of CEP85 to STIL ensures robust PLK4 activation and efficient centriole assembly.
Nat Commun, 9, 2018
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5OLM
 | | TRIM21 | | Descriptor: | E3 ubiquitin-protein ligase TRIM21, ZINC ION | | Authors: | James, L.C. | | Deposit date: | 2017-07-28 | | Release date: | 2018-04-25 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Intracellular antibody signalling is regulated by phosphorylation of the Fc receptor TRIM21.
Elife, 7, 2018
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5OI9
 | | Trichoplax adhaerens STIL N-terminal domain | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Putative uncharacterized protein | | Authors: | van Breugel, M. | | Deposit date: | 2017-07-18 | | Release date: | 2018-04-18 | | Last modified: | 2018-05-09 | | Method: | X-RAY DIFFRACTION (2.09 Å) | | Cite: | Direct binding of CEP85 to STIL ensures robust PLK4 activation and efficient centriole assembly.
Nat Commun, 9, 2018
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5OI7
 | | Human CEP85 - coiled coil domain 4 | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, Centrosomal protein of 85 kDa | | Authors: | van Breugel, M. | | Deposit date: | 2017-07-18 | | Release date: | 2018-04-18 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.67 Å) | | Cite: | Direct binding of CEP85 to STIL ensures robust PLK4 activation and efficient centriole assembly.
Nat Commun, 9, 2018
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4IRA
 | | CobR in complex with FAD | | Descriptor: | 4-hydroxyphenylacetate 3-monooxygenase, FLAVIN-ADENINE DINUCLEOTIDE, SULFATE ION | | Authors: | Lawrence, A.D, Scott, A.F, Warren, M.J, Pickersgill, R.W. | | Deposit date: | 2013-01-14 | | Release date: | 2014-01-29 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Biophysical characterisation and structure-function analysis of Brucella melitensis CobR: Protein-flavin interactions determine function and stability
To be Published
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6S6D
 | | Crystal structure of RagA-Q66L-GTP/RagC-S75N-GDP GTPase heterodimer complex | | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Anandapadamanaban, M, Masson, G.R, Perisic, O, Kaufman, J, Williams, R.L. | | Deposit date: | 2019-07-02 | | Release date: | 2019-10-16 | | Last modified: | 2024-05-15 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Architecture of human Rag GTPase heterodimers and their complex with mTORC1.
Science, 366, 2019
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6S6A
 | | Crystal structure of RagA-Q66L/RagC-T90N GTPase heterodimer complex | | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Anandapadamanaban, M, Masson, G.R, Perisic, O, Kaufman, J, Williams, R.L. | | Deposit date: | 2019-07-02 | | Release date: | 2019-10-16 | | Last modified: | 2024-05-15 | | Method: | X-RAY DIFFRACTION (2.63 Å) | | Cite: | Architecture of human Rag GTPase heterodimers and their complex with mTORC1.
Science, 366, 2019
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6SB2
 | | cryo-EM structure of mTORC1 bound to active RagA/C GTPases | | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Ras-related GTP-binding protein A, ... | | Authors: | Anandapadamanaban, M, Berndt, A, Masson, G.R, Perisic, O, Williams, R.L. | | Deposit date: | 2019-07-18 | | Release date: | 2019-10-16 | | Last modified: | 2024-05-22 | | Method: | ELECTRON MICROSCOPY (6.2 Å) | | Cite: | Architecture of human Rag GTPase heterodimers and their complex with mTORC1.
Science, 366, 2019
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6SB0
 | | cryo-EM structure of mTORC1 bound to PRAS40-fused active RagA/C GTPases | | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Proline-rich AKT1 substrate 1, ... | | Authors: | Anandapadamanaban, M, Berndt, A, Masson, G.R, Perisic, O, Williams, R.L. | | Deposit date: | 2019-07-18 | | Release date: | 2019-10-16 | | Last modified: | 2024-05-22 | | Method: | ELECTRON MICROSCOPY (5.5 Å) | | Cite: | Architecture of human Rag GTPase heterodimers and their complex with mTORC1.
Science, 366, 2019
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7O06
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7NWJ
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7O0S
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2Y3W
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2Y3V
 | | N-terminal head domain of Danio rerio SAS-6 | | Descriptor: | SPINDLE ASSEMBLY ABNORMAL PROTEIN 6 HOMOLOG | | Authors: | van Breugel, M. | | Deposit date: | 2010-12-27 | | Release date: | 2011-02-09 | | Last modified: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (1.92 Å) | | Cite: | Structures of SAS-6 suggest its organization in centrioles.
Science, 331, 2011
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4CZL
 | | C. crescentus MreB, monomeric, ADP | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ROD SHAPE-DETERMINING PROTEIN MREB | | Authors: | Lowe, J, van den Ent, F. | | Deposit date: | 2014-04-19 | | Release date: | 2014-06-25 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Bacterial Actin Mreb Forms Antiparallel Double Filaments.
Elife, 3, 2014
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4CZG
 | | C. crescentus MreB, single filament, ADP, A22 inhibitor | | Descriptor: | 3,4-dichlorobenzyl carbamimidothioate, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Lowe, J, van den Ent, F. | | Deposit date: | 2014-04-19 | | Release date: | 2014-06-11 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Bacterial Actin Mreb Forms Antiparallel Double Filaments.
Elife, 3, 2014
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4CZK
 | | C. crescentus MreB, single filament, AMPPNP, MP265 inhibitor | | Descriptor: | 4-chlorobenzyl carbamimidothioate, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | | Authors: | Lowe, J, van den Ent, F. | | Deposit date: | 2014-04-19 | | Release date: | 2014-06-11 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.602 Å) | | Cite: | Bacterial Actin Mreb Forms Antiparallel Double Filaments.
Elife, 3, 2014
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4CZJ
 | | C. crescentus MreB, double filament, AMPPNP | | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ROD SHAPE-DETERMINING PROTEIN MREB | | Authors: | Lowe, J, van den Ent, F. | | Deposit date: | 2014-04-19 | | Release date: | 2014-06-11 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Bacterial Actin Mreb Forms Antiparallel Double Filaments.
Elife, 3, 2014
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4CZI
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4CZH
 | | C. crescentus MreB, single filament, ADP, MP265 inhibitor | | Descriptor: | 4-chlorobenzyl carbamimidothioate, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Lowe, J, vandenEnt, F. | | Deposit date: | 2014-04-19 | | Release date: | 2014-06-11 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.644 Å) | | Cite: | Bacterial Actin Mreb Forms Antiparallel Double Filaments.
Elife, 3, 2014
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