6JAK
 
 | | OtsA apo structure | | Descriptor: | Trehalose-6-phosphate synthase | | Authors: | Wang, S, Zhao, Y, Wang, D, Liu, J. | | Deposit date: | 2019-01-24 | | Release date: | 2019-12-04 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.41 Å) | | Cite: | Crystal structures of Magnaporthe oryzae trehalose-6-phosphate synthase (MoTps1) suggest a model for catalytic process of Tps1.
Biochem.J., 476, 2019
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6JBI
 | | Structure of Tps1 apo structure | | Descriptor: | Trehalose-6-phosphate synthase | | Authors: | Wang, S, Zhao, Y, Yi, L, Wang, D, Liu, J. | | Deposit date: | 2019-01-25 | | Release date: | 2019-12-04 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal structures of Magnaporthe oryzae trehalose-6-phosphate synthase (MoTps1) suggest a model for catalytic process of Tps1.
Biochem.J., 476, 2019
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6C4Y
 | | Cross-alpha Amyloid-like Structure alphaAmG | | Descriptor: | Cross-alpha Amyloid-like Structure alphaAmG | | Authors: | Liu, L, Zhang, S.Q. | | Deposit date: | 2018-01-13 | | Release date: | 2018-08-15 | | Last modified: | 2019-12-18 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Designed peptides that assemble into cross-alpha amyloid-like structures.
Nat. Chem. Biol., 14, 2018
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6C4X
 | | Cross-alpha Amyloid-like Structure alphaAmmem | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, ZINC ION, cross-alpha amyloid-like membrane peptide alpha-AmMEM | | Authors: | Liu, L, Zhang, S.Q. | | Deposit date: | 2018-01-13 | | Release date: | 2018-08-15 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (3.55 Å) | | Cite: | Designed peptides that assemble into cross-alpha amyloid-like structures.
Nat. Chem. Biol., 14, 2018
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6C50
 | | Cross-alpha Amyloid-like Structure alphaAmS | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, Cross-alpha Amyloid-like Structure alphaAmS, FORMIC ACID | | Authors: | Liu, L, Zhang, S.Q. | | Deposit date: | 2018-01-13 | | Release date: | 2018-08-15 | | Last modified: | 2019-12-18 | | Method: | X-RAY DIFFRACTION (2.503 Å) | | Cite: | Designed peptides that assemble into cross-alpha amyloid-like structures.
Nat. Chem. Biol., 14, 2018
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6BLR
 | | Crystal Structure of IAg7 in complex with insulin mimotope p8E9E6SS | | Descriptor: | 1,2-ETHANEDIOL, H2-Ab1 protein, IAg7 alpha chain | | Authors: | Wang, Y, Dai, S. | | Deposit date: | 2017-11-11 | | Release date: | 2017-12-20 | | Last modified: | 2019-12-11 | | Method: | X-RAY DIFFRACTION (1.96 Å) | | Cite: | C-terminal modification of the insulin B:11-23 peptide creates superagonists in mouse and human type 1 diabetes.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6JBW
 | | Structure of Tps1/UDP complex | | Descriptor: | Trehalose-6-phosphate synthase, URIDINE-5'-DIPHOSPHATE | | Authors: | Wang, S, Zhao, Y, Wang, D, Liu, J. | | Deposit date: | 2019-01-26 | | Release date: | 2019-12-04 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.65 Å) | | Cite: | Crystal structures of Magnaporthe oryzae trehalose-6-phosphate synthase (MoTps1) suggest a model for catalytic process of Tps1.
Biochem.J., 476, 2019
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6C4Z
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6JLQ
 | | Crystal structure of human USP46-WDR48-WDR20 complex | | Descriptor: | GLYCEROL, PHOSPHATE ION, Ubiquitin carboxyl-terminal hydrolase 46, ... | | Authors: | Zhu, H, Zhang, T, Ding, J. | | Deposit date: | 2019-03-06 | | Release date: | 2019-07-10 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (3.101 Å) | | Cite: | Structural insights into the activation of USP46 by WDR48 and WDR20.
Cell Discov, 5, 2019
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6C52
 | | Cross-alpha Amyloid-like Structure alphaTet | | Descriptor: | Cross-alpha Amyloid-like Structure alphaTet, GLYCEROL | | Authors: | Liu, L, Zhang, S.Q. | | Deposit date: | 2018-01-13 | | Release date: | 2018-08-15 | | Last modified: | 2020-01-01 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Designed peptides that assemble into cross-alpha amyloid-like structures.
Nat. Chem. Biol., 14, 2018
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6C51
 | | Cross-alpha Amyloid-like Structure alphaAmL | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, Cross-alpha Amyloid-like Structure alphaAmL, PHOSPHATE ION | | Authors: | Liu, L, Zhang, S.Q. | | Deposit date: | 2018-01-13 | | Release date: | 2018-08-15 | | Last modified: | 2019-12-18 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Designed peptides that assemble into cross-alpha amyloid-like structures.
Nat. Chem. Biol., 14, 2018
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7DCL
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6D02
 | | Cross-alpha Amyloid-like Structure alphaAmL, 2nd form | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, CARBONATE ION, PHOSPHATE ION, ... | | Authors: | Zhang, S.-Q, Liu, L, Degrado, W.F. | | Deposit date: | 2018-04-10 | | Release date: | 2019-02-20 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Designed peptides that assemble into cross-alpha amyloid-like structures.
Nat. Chem. Biol., 14, 2018
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7L5S
 | | Crystal Structure of Haemophilus influenzae MtsZ at pH 5.5 | | Descriptor: | 2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE GUANOSINE DINUCLEOTIDE, MOLYBDENUM ATOM, OXYGEN ATOM, ... | | Authors: | Struwe, M.A, Luo, Z, Kappler, U, Kobe, B. | | Deposit date: | 2020-12-22 | | Release date: | 2021-04-21 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.089 Å) | | Cite: | Active site architecture reveals coordination sphere flexibility and specificity determinants in a group of closely related molybdoenzymes.
J.Biol.Chem., 296, 2021
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7L5I
 | | Crystal Structure of Haemophilus influenzae MtsZ at pH 7.0 | | Descriptor: | 2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE GUANOSINE DINUCLEOTIDE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, ... | | Authors: | Struwe, M.A, Luo, Z, Kappler, U, Kobe, B. | | Deposit date: | 2020-12-22 | | Release date: | 2021-04-21 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.733 Å) | | Cite: | Active site architecture reveals coordination sphere flexibility and specificity determinants in a group of closely related molybdoenzymes.
J.Biol.Chem., 296, 2021
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6DDI
 | | Crystal Structure of the human BRD2 BD1 bromodomain in complex with a Tetrahydroquinoline analogue | | Descriptor: | 1,2-ETHANEDIOL, 4-{[(2S,4R)-1-acetyl-2-methyl-6-(1H-pyrazol-3-yl)-1,2,3,4-tetrahydroquinolin-4-yl]amino}benzonitrile, Bromodomain-containing protein 2, ... | | Authors: | White, S.W, Yun, M. | | Deposit date: | 2018-05-10 | | Release date: | 2019-11-13 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Bromodomain-Selective BET Inhibitors Are Potent Antitumor Agents against MYC-Driven Pediatric Cancer.
Cancer Res., 80, 2020
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6DDJ
 | | Crystal Structure of the human BRD2 BD2 bromodimain in complex with a Tetrahydroquinoline analogue | | Descriptor: | 1,2-ETHANEDIOL, 4-{[(2S,4R)-1-acetyl-2-methyl-6-(1H-pyrazol-3-yl)-1,2,3,4-tetrahydroquinolin-4-yl]amino}benzonitrile, Bromodomain-containing protein 2 | | Authors: | White, S.W, Yun, M. | | Deposit date: | 2018-05-10 | | Release date: | 2019-11-13 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.05 Å) | | Cite: | Bromodomain-Selective BET Inhibitors Are Potent Antitumor Agents against MYC-Driven Pediatric Cancer.
Cancer Res., 80, 2020
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7L4X
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7L4Y
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6LDF
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6LDE
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6LDG
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1SZJ
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6J1M
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6J1N
 | | Anisodus acutangulus type III polyketide sythase AaPKS2 in complex with 4-carboxy-3-oxobutanoyl-CoA | | Descriptor: | (3R,5R,9R)-1-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]-3,5,9-trihydroxy-8,8-dimethyl-10,14,19,21-tetraoxo-2,4,6-trioxa-18-thia-11,15-diaza-3,5-diphosphatricosan-23-oic acid 3,5-dioxide (non-preferred name), A. acutangulus PKS2 | | Authors: | Fang, C.L, Zhang, Y. | | Deposit date: | 2018-12-28 | | Release date: | 2019-09-11 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.532 Å) | | Cite: | Tropane alkaloids biosynthesis involves an unusual type III polyketide synthase and non-enzymatic condensation.
Nat Commun, 10, 2019
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