6VXZ
| SthK P300A cyclic nucleotide-gated potassium channel in the closed state, in complex with cAMP | Descriptor: | (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, SthK | Authors: | Schmidpeter, P.A.M, Rheinberger, J, Nimigean, C.M. | Deposit date: | 2020-02-25 | Release date: | 2020-11-11 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.42 Å) | Cite: | Prolyl isomerization controls activation kinetics of a cyclic nucleotide-gated ion channel. Nat Commun, 11, 2020
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6VY0
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8PCZ
| Ligand-free SpSLC9C1 in lipid nanodiscs, dimer | Descriptor: | Sperm-specific sodium proton exchanger | Authors: | Kalienkova, V, Peter, M, Rheinberger, J, Paulino, C. | Deposit date: | 2023-06-11 | Release date: | 2023-11-08 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (3.21 Å) | Cite: | Structures of a sperm-specific solute carrier gated by voltage and cAMP. Nature, 623, 2023
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8PD2
| Ligand-free SpSLC9C1 in lipid nanodiscs, protomer state 1 | Descriptor: | Sperm-specific sodium proton exchanger | Authors: | Kalienkova, V, Peter, M, Rheinberger, J, Paulino, C. | Deposit date: | 2023-06-11 | Release date: | 2023-11-08 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (3.25 Å) | Cite: | Structures of a sperm-specific solute carrier gated by voltage and cAMP. Nature, 623, 2023
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8PD9
| cAMP-bound SpSLC9C1 in lipid nanodiscs, protomer state 1 | Descriptor: | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Sperm-specific sodium proton exchanger | Authors: | Kalienkova, V, Peter, M, Rheinberger, J, Paulino, C. | Deposit date: | 2023-06-12 | Release date: | 2023-11-08 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structures of a sperm-specific solute carrier gated by voltage and cAMP. Nature, 623, 2023
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8PDV
| cGMP-bound SpSLC9C1 in lipid nanodiscs, protomer | Descriptor: | CYCLIC GUANOSINE MONOPHOSPHATE, Sperm-specific sodium proton exchanger | Authors: | Kalienkova, V, Peter, M, Rheinberger, J, Paulino, C. | Deposit date: | 2023-06-12 | Release date: | 2023-11-08 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (3.26 Å) | Cite: | Structures of a sperm-specific solute carrier gated by voltage and cAMP. Nature, 623, 2023
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8PD7
| Ligand-free SpSLC9C1 in lipid nanodiscs, protomer state 4 | Descriptor: | Sperm-specific sodium proton exchanger | Authors: | Kalienkova, V, Peter, M, Rheinberger, J, Paulino, C. | Deposit date: | 2023-06-11 | Release date: | 2023-11-08 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structures of a sperm-specific solute carrier gated by voltage and cAMP. Nature, 623, 2023
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8PDU
| cGMP-bound SpSLC9C1 in lipid nanodiscs, dimer | Descriptor: | CYCLIC GUANOSINE MONOPHOSPHATE, Sperm-specific sodium proton exchanger | Authors: | Kalienkova, V, Peter, M, Rheinberger, J, Paulino, C. | Deposit date: | 2023-06-12 | Release date: | 2023-11-08 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (3.22 Å) | Cite: | Structures of a sperm-specific solute carrier gated by voltage and cAMP. Nature, 623, 2023
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8PD5
| Ligand-free SpSLC9C1 in lipid nanodiscs, protomer state 3 | Descriptor: | Sperm-specific sodium proton exchanger | Authors: | Kalienkova, V, Peter, M, Rheinberger, J, Paulino, C. | Deposit date: | 2023-06-11 | Release date: | 2023-11-08 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structures of a sperm-specific solute carrier gated by voltage and cAMP. Nature, 623, 2023
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8PD3
| Ligand-free SpSLC9C1 in lipid nanodiscs, protomer state 2 | Descriptor: | Sperm-specific sodium proton exchanger | Authors: | Kalienkova, V, Peter, M, Rheinberger, J, Paulino, C. | Deposit date: | 2023-06-11 | Release date: | 2023-11-08 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structures of a sperm-specific solute carrier gated by voltage and cAMP. Nature, 623, 2023
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7ZRG
| Cryo-EM map of the WT KdpFABC complex in the E1_ATPearly conformation, under turnover conditions | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, CARDIOLIPIN, POTASSIUM ION, ... | Authors: | Hielkema, L, Stock, C, Silberberg, J.M, Corey, R.A, Rheinberger, J, Wunnicke, D, Dubach, V.R.A, Stansfeld, P.J, Haenelt, I, Paulino, C. | Deposit date: | 2022-05-04 | Release date: | 2022-11-16 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Inhibited KdpFABC transitions into an E1 off-cycle state. Elife, 11, 2022
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6E1O
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6E0H
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6DZ7
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7TJ5
| SthK closed state, cAMP-bound in the presence of POPA | Descriptor: | (2R)-1-(hexadecanoyloxy)-3-(phosphonooxy)propan-2-yl (9Z)-octadec-9-enoate, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Putative transcriptional regulator, ... | Authors: | Schmidpeter, P.A, Nimigean, C.M. | Deposit date: | 2022-01-14 | Release date: | 2022-10-26 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (2.41 Å) | Cite: | Anionic lipids unlock the gates of select ion channels in the pacemaker family. Nat.Struct.Mol.Biol., 29, 2022
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7TJ6
| SthK open state, cAMP-bound in the presence of POPA | Descriptor: | (2R)-1-(hexadecanoyloxy)-3-(phosphonooxy)propan-2-yl (9Z)-octadec-9-enoate, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Putative transcriptional regulator, ... | Authors: | Schmidpeter, P.A, Nimigean, C.M. | Deposit date: | 2022-01-14 | Release date: | 2022-10-26 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Anionic lipids unlock the gates of select ion channels in the pacemaker family. Nat.Struct.Mol.Biol., 29, 2022
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6U6H
| Calcium-bound MthK open-inactivated state 3 | Descriptor: | Calcium-gated potassium channel MthK | Authors: | Chen, F, Crina, N. | Deposit date: | 2019-08-29 | Release date: | 2020-04-22 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (5 Å) | Cite: | Ball-and-chain inactivation in a calcium-gated potassium channel. Nature, 580, 2020
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6U5R
| Calcium-bound MthK closed state | Descriptor: | CALCIUM ION, Calcium-gated potassium channel MthK | Authors: | Fan, C, Nimigean, C.M. | Deposit date: | 2019-08-28 | Release date: | 2020-03-25 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Ball-and-chain inactivation in a calcium-gated potassium channel. Nature, 580, 2020
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6U5P
| Calcium-bound MthK gating ring state 1 | Descriptor: | CALCIUM ION, Calcium-gated potassium channel MthK | Authors: | Fan, C, Nimigean, C.M. | Deposit date: | 2019-08-28 | Release date: | 2020-03-25 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Ball-and-chain inactivation in a calcium-gated potassium channel. Nature, 580, 2020
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8FZ7
| TpeA bound closed MthK-A88F mutant in nanodisc | Descriptor: | (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, 1-(tripentyl-$l^{4}-azanyl)pentane, Calcium-gated potassium channel MthK, ... | Authors: | Agarwal, S, Nimigean, C.M. | Deposit date: | 2023-01-27 | Release date: | 2023-10-11 | Last modified: | 2024-01-03 | Method: | ELECTRON MICROSCOPY (2.88 Å) | Cite: | Calcium-gated potassium channel blockade via membrane-facing fenestrations. Nat.Chem.Biol., 20, 2024
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6U68
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6U5N
| Calcium-bound MthK gating ring state 2 | Descriptor: | CALCIUM ION, Calcium-gated potassium channel MthK | Authors: | Fan, C, Nimigean, C.M. | Deposit date: | 2019-08-28 | Release date: | 2020-03-25 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Ball-and-chain inactivation in a calcium-gated potassium channel. Nature, 580, 2020
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6U6E
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6UXB
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6UXA
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