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5JWK
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BU of 5jwk by Molmil
Factor Inhibiting HIF D201E in Complex with Fe, and Alpha-Ketoglutarate
Descriptor: 2-OXOGLUTARIC ACID, DI(HYDROXYETHYL)ETHER, FE (II) ION, ...
Authors:Taabazuing, C.Y, Garman, S.C, Knapp, M.J, Eron, S.
Deposit date:2016-05-12
Release date:2017-05-17
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Factor Inhibiting HIF D201E in Complex with Fe, and Alpha-Ketoglutarate
To Be Published
5KZX
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BU of 5kzx by Molmil
Crystal structure of human GAA
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Deming, D.T, Garman, S.C.
Deposit date:2016-07-25
Release date:2017-07-26
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:The structure of human GAA: structural basis of Pompe disease
To be published
5KZW
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BU of 5kzw by Molmil
Crystal structure of human GAA
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Deming, D.T, Garman, S.C.
Deposit date:2016-07-25
Release date:2017-07-26
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:The structure of human GAA: structural basis of Pompe disease
To be published
1YPY
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BU of 1ypy by Molmil
Crystal Structure of Vaccinia Virus L1 protein
Descriptor: Virion membrane protein
Authors:Su, H.P, Garman, S.C, Allison, T.J, Fogg, C, Moss, B, Garboczi, D.N.
Deposit date:2005-01-31
Release date:2005-03-01
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.51 Å)
Cite:The 1.51-Angstrom structure of the poxvirus L1 protein, a target of potent neutralizing antibodies.
Proc.Natl.Acad.Sci.Usa, 102, 2005
7KL2
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BU of 7kl2 by Molmil
Cocrystal structure of human CaMKII-alpha (CAMK2A)kinase domain and GluN2B(S1303D)
Descriptor: Calcium/calmodulin-dependent protein kinase type II subunit alpha, Glutamate receptor ionotropic, NMDA 2B
Authors:Ozden, C, Stratton, M.M, Garman, S.C.
Deposit date:2020-10-28
Release date:2020-12-23
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.56 Å)
Cite:Cocrystal structure of human CaMKII-alpha (CAMK2A)kinase domain and GluN2B(S1303D)
To Be Published
7KL1
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BU of 7kl1 by Molmil
Cocrystal structure of human CaMKII-alpha (CAMK2A)kinase domain and GluN2B(S1303D)
Descriptor: 1,2-ETHANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, Calcium/calmodulin-dependent protein kinase type II subunit alpha, ...
Authors:Ozden, C, Stratton, M.M, Garman, S.C.
Deposit date:2020-10-28
Release date:2020-12-23
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:CaMKII binds both substrates and activators at the active site.
Cell Rep, 40, 2022
7KL0
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BU of 7kl0 by Molmil
Cocrystal structure of human CaMKII-alpha (CAMK2A)kinase domain and GluN2B(S1303D)
Descriptor: 1,2-ETHANEDIOL, Calcium/calmodulin-dependent protein kinase type II subunit alpha, Glutamate receptor ionotropic, ...
Authors:Ozden, C, Stratton, M.M, Garman, S.C.
Deposit date:2020-10-28
Release date:2020-12-23
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:CaMKII binds both substrates and activators at the active site.
Cell Rep, 40, 2022
4MWS
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BU of 4mws by Molmil
Crystal structure of human PPCA (trigonal crystal form 1)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Lysosomal protective protein, ...
Authors:Kolli, N, Garman, S.C.
Deposit date:2013-09-25
Release date:2014-03-12
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Proteolytic activation of human cathepsin A.
J.Biol.Chem., 289, 2014
4MWT
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BU of 4mwt by Molmil
Crystal structure of human PPCA (trigonal crystal form 2)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Lysosomal protective protein, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Kolli, N, Garman, S.C.
Deposit date:2013-09-25
Release date:2014-03-12
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.85 Å)
Cite:Proteolytic activation of human cathepsin A.
J.Biol.Chem., 289, 2014
1FP5
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BU of 1fp5 by Molmil
CRYSTAL STRUCTURE ANALYSIS OF THE HUMAN IGE-FC CEPSILON3-CEPSILON4 FRAGMENT.
Descriptor: IGE HEAVY CHAIN EPSILON-1
Authors:Wurzburg, B.A, Garman, S.C, Jardetzky, T.S.
Deposit date:2000-08-30
Release date:2000-09-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of the human IgE-Fc C epsilon 3-C epsilon 4 reveals conformational flexibility in the antibody effector domains.
Immunity, 13, 2000
7UIS
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BU of 7uis by Molmil
Cocrystal structure of human CaMKII-alpha (CAMK2A)kinase domain and GluN2B(S1303D)
Descriptor: Calcium/calmodulin-dependent protein kinase type II subunit alpha, Glutamate receptor ionotropic, NMDA 2B
Authors:Ozden, C, Stratton, M.M, Garman, S.C.
Deposit date:2022-03-29
Release date:2022-04-06
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.58 Å)
Cite:CaMKII binds both substrates and activators at the active site.
Cell Rep, 40, 2022
7UIR
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BU of 7uir by Molmil
Cocrystal structure of human CaMKII-alpha (CAMK2A)kinase domain and Tiam1 in complex with ATP
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ADENOSINE-5'-TRIPHOSPHATE, Calcium/calmodulin-dependent protein kinase type II subunit alpha, ...
Authors:Ozden, C, Stratton, M.M, Garman, S.C.
Deposit date:2022-03-29
Release date:2022-04-06
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:CaMKII binds both substrates and activators at the active site.
Cell Rep, 40, 2022
7UIQ
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BU of 7uiq by Molmil
Cocrystal structure of human CaMKII-alpha (CAMK2A)kinase domain and Tiam1
Descriptor: Calcium/calmodulin-dependent protein kinase type II subunit alpha, T-lymphoma invasion and metastasis-inducing protein 1
Authors:Ozden, C, Stratton, M.M, Garman, S.C.
Deposit date:2022-03-29
Release date:2022-04-06
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.11 Å)
Cite:CaMKII binds both substrates and activators at the active site.
Cell Rep, 40, 2022
7UJP
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BU of 7ujp by Molmil
Cocrystal structure of human CaMKII-alpha (CAMK2A)kinase domain and GluN2B
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Calcium/calmodulin-dependent protein kinase type II subunit alpha, ...
Authors:Ozden, C, Foster, J.C, Stratton, M.M, Garman, S.C.
Deposit date:2022-03-31
Release date:2022-04-13
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.56 Å)
Cite:CaMKII binds both substrates and activators at the active site.
Cell Rep, 40, 2022
7UJT
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BU of 7ujt by Molmil
Cocrystal structure of human CaMKII-alpha (CAMK2A)kinase domain and GluN2B(S1303D) in complex with ATP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Calcium/calmodulin-dependent protein kinase type II subunit alpha, GLYCEROL, ...
Authors:Ozden, C, Stratton, M.M, Garman, S.C.
Deposit date:2022-03-31
Release date:2022-04-13
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:CaMKII binds both substrates and activators at the active site.
Cell Rep, 40, 2022
7UJS
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BU of 7ujs by Molmil
Cocrystal structure of human CaMKII-alpha (CAMK2A)kinase domain and GluN2B in complex with ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Calcium/calmodulin-dependent protein kinase type II subunit alpha, Glutamate receptor ionotropic, ...
Authors:Ozden, C, Santos, N.J, Stratton, M.M, Garman, S.C.
Deposit date:2022-03-31
Release date:2022-04-13
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:CaMKII binds both substrates and activators at the active site.
Cell Rep, 40, 2022
7UJQ
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BU of 7ujq by Molmil
Cocrystal structure of human CaMKII-alpha (CAMK2A)kinase domain and GluN2B
Descriptor: Calcium/calmodulin-dependent protein kinase type II subunit alpha, GLYCEROL, Glutamate receptor ionotropic, ...
Authors:Ozden, C, Foster, J.C, Stratton, M.M, Garman, S.C.
Deposit date:2022-03-31
Release date:2022-04-13
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:CaMKII binds both substrates and activators at the active site.
Cell Rep, 40, 2022
7UJR
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BU of 7ujr by Molmil
Cocrystal structure of human CaMKII-alpha (CAMK2A)kinase domain and GluN2B
Descriptor: 1,2-ETHANEDIOL, Calcium/calmodulin-dependent protein kinase type II subunit alpha, Glutamate receptor ionotropic, ...
Authors:Ozden, C, Santos, N.J, Stratton, M.M, Garman, S.C.
Deposit date:2022-03-31
Release date:2022-04-13
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:CaMKII binds both substrates and activators at the active site.
Cell Rep, 40, 2022
7URW
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BU of 7urw by Molmil
Tetradecameric hub domain of CaMKII beta
Descriptor: Calcium/calmodulin-dependent protein kinase type II subunit beta
Authors:Ozden, C, Samkutty, A, Stratton, M.M, Garman, S.C.
Deposit date:2022-04-22
Release date:2022-05-11
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.11 Å)
Cite:Tetradecameric hub domain of CaMKII beta
To Be Published
7URZ
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BU of 7urz by Molmil
Hexadecameric hub domain of CaMKII beta
Descriptor: Calcium/calmodulin-dependent protein kinase type II subunit beta
Authors:Ozden, C, Samkutty, A, Stratton, M.M, Garman, S.C.
Deposit date:2022-04-22
Release date:2022-05-11
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.45 Å)
Cite:Hexadecameric hub domain of CaMKII beta
To Be Published
3S5Y
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BU of 3s5y by Molmil
Pharmacological Chaperoning in Human alpha-Galactosidase
Descriptor: (2R,3S,4R,5S)-2-(hydroxymethyl)piperidine-3,4,5-triol, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Guce, A.I, Clark, N.E, Garman, S.C.
Deposit date:2011-05-23
Release date:2012-01-04
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.105 Å)
Cite:The molecular basis of pharmacological chaperoning in human alpha-galactosidase
Chem.Biol., 18, 2011
3S5Z
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BU of 3s5z by Molmil
Pharmacological Chaperoning in Human alpha-Galactosidase
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-galactosidase A, GLYCEROL, ...
Authors:Guce, A.I, Clark, N.E, Garman, S.C.
Deposit date:2011-05-23
Release date:2012-01-04
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.001 Å)
Cite:The molecular basis of pharmacological chaperoning in human alpha-galactosidase
Chem.Biol., 18, 2011
3U2A
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BU of 3u2a by Molmil
Adaptor dependent degradation of a cell-cycle regulator reveals diversity in substrate architectures
Descriptor: GGDEF family protein
Authors:Rood, K, Clark, N.E, Garman, S.C, Chien, P.
Deposit date:2011-10-02
Release date:2012-05-30
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Adaptor-dependent degradation of a cell-cycle regulator uses a unique substrate architecture.
Structure, 20, 2012
3H55
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BU of 3h55 by Molmil
Crystal Structure of human alpha-N-acetylgalactosaminidase, Complex with Galactose
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-N-acetylgalactosaminidase, ...
Authors:Clark, N.E, Garman, S.C.
Deposit date:2009-04-21
Release date:2009-10-20
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:The 1.9 a structure of human alpha-N-acetylgalactosaminidase: The molecular basis of Schindler and Kanzaki diseases
J.Mol.Biol., 393, 2009
3H53
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BU of 3h53 by Molmil
Crystal Structure of human alpha-N-acetylgalactosaminidase
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-N-acetylgalactosaminidase, ...
Authors:Clark, N.E, Garman, S.C.
Deposit date:2009-04-21
Release date:2009-10-20
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:The 1.9 a structure of human alpha-N-acetylgalactosaminidase: The molecular basis of Schindler and Kanzaki diseases
J.Mol.Biol., 393, 2009

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