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2IYC
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BU of 2iyc by Molmil
SENP1 native structure
Descriptor: SENTRIN-SPECIFIC PROTEASE 1
Authors:Dong, C, Naismith, J.H.
Deposit date:2006-07-14
Release date:2006-08-08
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Senp1 Native Structure
To be Published
2IYD
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BU of 2iyd by Molmil
SENP1 covalent complex with SUMO-2
Descriptor: SENTRIN-SPECIFIC PROTEASE 1, SMALL UBIQUITIN-RELATED MODIFIER 2
Authors:Dong, C, Naismith, J.H.
Deposit date:2006-07-14
Release date:2006-08-08
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Senp1 Native Structure
To be Published
2IXH
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BU of 2ixh by Molmil
RmlC P aeruginosa with dTDP-rhamnose
Descriptor: 2'-DEOXY-THYMIDINE-BETA-L-RHAMNOSE, DTDP-4-DEHYDRORHAMNOSE 3,5-EPIMERASE
Authors:Dong, C, Naismith, J.H.
Deposit date:2006-07-08
Release date:2006-10-26
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:RmlC, a C3' and C5' carbohydrate epimerase, appears to operate via an intermediate with an unusual twist boat conformation.
J. Mol. Biol., 365, 2007
2IXL
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BU of 2ixl by Molmil
RmlC S. suis with dTDP-rhamnose
Descriptor: 2'-DEOXY-THYMIDINE-BETA-L-RHAMNOSE, DTDP-4-DEHYDRORHAMNOSE 3,5-EPIMERASE, NICKEL (II) ION
Authors:Dong, C, Naismith, J.H.
Deposit date:2006-07-08
Release date:2006-10-26
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Rmlc, a C3' and C5' Carbohydrate Epimerase, Appears to Operate Via an Intermediate with an Unusual Twist Boat Conformation.
J.Mol.Biol., 365, 2007
2IXC
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BU of 2ixc by Molmil
RmlC M. tuberculosis with dTDP-rhamnose
Descriptor: 2'-DEOXY-THYMIDINE-BETA-L-RHAMNOSE, DTDP-4-DEHYDRORHAMNOSE 3,5-EPIMERASE RMLC
Authors:Dong, C, Naismith, J.H.
Deposit date:2006-07-07
Release date:2006-10-26
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Rmlc, a C3' and C5' Carbohydrate Epimerase, Appears to Operate Via an Intermediate with an Unusual Twist Boat Conformation.
J.Mol.Biol., 365, 2007
2IXK
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BU of 2ixk by Molmil
RmlC P aeruginosa with dTDP-4-keto rhamnnose (the product of the reaction)
Descriptor: DTDP-4-DEHYDRORHAMNOSE 3,5-EPIMERASE, DTDP-4-KETO-L-RHAMNOSE
Authors:Dong, C, Naismith, J.H.
Deposit date:2006-07-08
Release date:2006-08-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Rmlc, a C3' and C5' Carbohydrate Epimerase, Appears to Operate Via an Intermediate with an Unusual Twist Boat Conformation.
J.Mol.Biol., 365, 2007
2J58
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BU of 2j58 by Molmil
The structure of Wza
Descriptor: HEXANE, N-OCTANE, OUTER MEMBRANE LIPOPROTEIN WZA, ...
Authors:Dong, C, Naismith, J.H.
Deposit date:2006-09-12
Release date:2006-11-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Wza the Translocon for E. Coli Capsular Polysaccharides Defines a New Class of Membrane Protein.
Nature, 444, 2006
2IXI
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BU of 2ixi by Molmil
RmlC P aeruginosa with dTDP-xylose
Descriptor: DTDP-4-DEHYDRORHAMNOSE 3,5-EPIMERASE, S,R MESO-TARTARIC ACID, THYMIDINE-5'-DIPHOSPHATE
Authors:Dong, C, Naismith, J.H.
Deposit date:2006-07-08
Release date:2006-07-11
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Rmlc, a C3' and C5' Carbohydrate Epimerase, Appears to Operate Via an Intermediate with an Unusual Twist Boat Conformation.
J.Mol.Biol., 365, 2007
2IXJ
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BU of 2ixj by Molmil
RmlC P aeruginosa native
Descriptor: DTDP-4-DEHYDRORHAMNOSE 3,5-EPIMERASE, S,R MESO-TARTARIC ACID
Authors:Dong, C, Naismith, J.H.
Deposit date:2006-07-08
Release date:2006-07-11
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.54 Å)
Cite:Rmlc, a C3' and C5' Carbohydrate Epimerase, Appears to Operate Via an Intermediate with an Unusual Twist Boat Conformation.
J.Mol.Biol., 365, 2007
6CDG
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BU of 6cdg by Molmil
GID4 fragment in complex with a peptide
Descriptor: Glucose-induced degradation protein 4 homolog, Hexapeptide PGLWKS, UNKNOWN ATOM OR ION
Authors:Dong, C, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2018-02-08
Release date:2018-03-07
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Molecular basis of GID4-mediated recognition of degrons for the Pro/N-end rule pathway.
Nat. Chem. Biol., 14, 2018
6CD8
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BU of 6cd8 by Molmil
Complex of GID4 fragment with short peptide
Descriptor: Glucose-induced degradation protein 4 homolog, Tetrapeptide PSRV, UNKNOWN ATOM OR ION
Authors:Dong, C, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2018-02-08
Release date:2018-03-07
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Molecular basis of GID4-mediated recognition of degrons for the Pro/N-end rule pathway.
Nat. Chem. Biol., 14, 2018
6CDC
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BU of 6cdc by Molmil
GID4 in complex with a tetrapeptide
Descriptor: Glucose-induced degradation protein 4 homolog, Tetrapeptide PGLW, UNKNOWN ATOM OR ION
Authors:Dong, C, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2018-02-08
Release date:2018-03-07
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Molecular basis of GID4-mediated recognition of degrons for the Pro/N-end rule pathway.
Nat. Chem. Biol., 14, 2018
6CCR
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BU of 6ccr by Molmil
Selenomethionyl derivative of a GID4 fragment
Descriptor: Glucose-induced degradation protein 4 homolog, UNKNOWN ATOM OR ION
Authors:Dong, C, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2018-02-07
Release date:2018-04-04
Last modified:2018-04-25
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Molecular basis of GID4-mediated recognition of degrons for the Pro/N-end rule pathway.
Nat. Chem. Biol., 14, 2018
6CCU
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BU of 6ccu by Molmil
Complex between a GID4 fragment and a short peptide
Descriptor: Glucose-induced degradation protein 4 homolog, Short peptide, UNKNOWN ATOM OR ION
Authors:Dong, C, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2018-02-07
Release date:2018-03-07
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Molecular basis of GID4-mediated recognition of degrons for the Pro/N-end rule pathway.
Nat. Chem. Biol., 14, 2018
6CD9
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BU of 6cd9 by Molmil
GID4 in complex with a peptide
Descriptor: Glucose-induced degradation protein 4 homolog, Tetrapeptide PSRW, UNKNOWN ATOM OR ION
Authors:Dong, C, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2018-02-08
Release date:2018-03-07
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Molecular basis of GID4-mediated recognition of degrons for the Pro/N-end rule pathway.
Nat. Chem. Biol., 14, 2018
6CCT
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BU of 6cct by Molmil
Fragment of GID4 in complex with a short peptide
Descriptor: Glucose-induced degradation protein 4 homolog, Tetrapeptide
Authors:Dong, C, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2018-02-07
Release date:2018-03-07
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Molecular basis of GID4-mediated recognition of degrons for the Pro/N-end rule pathway.
Nat. Chem. Biol., 14, 2018
5E1M
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BU of 5e1m by Molmil
Crystal structure of NTMT1 in complex with PPKRIA peptide
Descriptor: GLYCEROL, N-terminal Xaa-Pro-Lys N-methyltransferase 1, RCC1, ...
Authors:Dong, C, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2015-09-29
Release date:2015-10-28
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural basis for substrate recognition by the human N-terminal methyltransferase 1.
Genes Dev., 29, 2015
5E2A
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BU of 5e2a by Molmil
Crystal structure of NTMT1 in complex with N-terminally methylated SPKRIA peptide
Descriptor: GLYCEROL, N-terminal Xaa-Pro-Lys N-methyltransferase 1, RCC1, ...
Authors:Dong, C, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2015-09-30
Release date:2015-10-28
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural basis for substrate recognition by the human N-terminal methyltransferase 1.
Genes Dev., 29, 2015
5E1B
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BU of 5e1b by Molmil
Crystal structure of NRMT1 in complex with SPKRIA peptide
Descriptor: GLYCEROL, N-terminal Xaa-Pro-Lys N-methyltransferase 1, RCC1, ...
Authors:Dong, C, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2015-09-29
Release date:2015-10-28
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structural basis for substrate recognition by the human N-terminal methyltransferase 1.
Genes Dev., 29, 2015
5E2B
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BU of 5e2b by Molmil
Crystal structure of NTMT1 in complex with N-terminally methylated PPKRIA peptide
Descriptor: GLYCEROL, N-terminal Xaa-Pro-Lys N-methyltransferase 1, RCC1, ...
Authors:Dong, C, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2015-09-30
Release date:2015-10-28
Last modified:2015-12-02
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural basis for substrate recognition by the human N-terminal methyltransferase 1.
Genes Dev., 29, 2015
5E1D
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BU of 5e1d by Molmil
NTMT1 in complex with YPKRIA peptide
Descriptor: GLYCEROL, N-terminal Xaa-Pro-Lys N-methyltransferase 1, RCC1, ...
Authors:Dong, C, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2015-09-29
Release date:2015-10-28
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Structural basis for substrate recognition by the human N-terminal methyltransferase 1.
Genes Dev., 29, 2015
5E1O
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BU of 5e1o by Molmil
Crystal structure of NTMT1 in complex with RPKRIA peptide
Descriptor: GLYCEROL, N-terminal Xaa-Pro-Lys N-methyltransferase 1, RCC1, ...
Authors:Dong, C, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2015-09-29
Release date:2015-10-28
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for substrate recognition by the human N-terminal methyltransferase 1.
Genes Dev., 29, 2015
4XFV
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BU of 4xfv by Molmil
Crystal Structure of Elp2
Descriptor: Elongator complex protein 2
Authors:Lin, Z, Dong, C, Long, J, Shen, Y.
Deposit date:2014-12-29
Release date:2015-05-20
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:The elp2 subunit is essential for elongator complex assembly and functional regulation
Structure, 23, 2015
5L75
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BU of 5l75 by Molmil
A protein structure
Descriptor: FIG000906: Predicted Permease, FIG000988: Predicted permease, Lipopolysaccharide ABC transporter, ...
Authors:Dong, C, Dong, H, Zhang, Z, Paterson, N, Tang, X.
Deposit date:2016-06-01
Release date:2017-08-16
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Structural and functional insights into the lipopolysaccharide ABC transporter LptB2FG.
Nat Commun, 8, 2017
1PM7
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BU of 1pm7 by Molmil
RmlC (dTDP-6-DEOXY-D-XYLO-4-HEXULOSE 3,5-EPIMERASE)STRUCTURE FROM MYCOBACTERIUM TUBERCULOSIS AND INHIBITOR DESIGN. THE APO STRUCTURE.
Descriptor: ACETATE ION, GLYCEROL, RFBC
Authors:Dong, C, Naismith, J.H, TB Structural Genomics Consortium (TBSGC)
Deposit date:2003-06-10
Release date:2003-12-09
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Novel inhibitors of an emerging target in Mycobacterium tuberculosis; substituted thiazolidinones as inhibitors of dTDP-rhamnose synthesis.
Bioorg.Med.Chem.Lett., 13, 2003

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