4JD6
 
 | | Crystal structure of Mycobacterium tuberculosis Eis in complex with coenzyme A and tobramycin | | Descriptor: | COENZYME A, Enhanced intracellular survival protein, TOBRAMYCIN | | Authors: | Biswas, T, Chen, W, Garneau-Tsodikova, S, Tsodikov, O.V. | | Deposit date: | 2013-02-23 | | Release date: | 2013-10-23 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Chemical and structural insights into the regioversatility of the aminoglycoside acetyltransferase eis.
Chembiochem, 14, 2013
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5EBZ
 | | Crystal structure of human IKK1 | | Descriptor: | 2,3-di-O-sulfo-alpha-D-glucopyranose-(1-6)-alpha-D-glucopyranose-(1-6)-2,4-di-O-sulfo-alpha-D-glucopyranose, 2-azanyl-5-phenyl-3-(4-sulfamoylphenyl)benzamide, Inhibitor of nuclear factor kappa-B kinase subunit alpha, ... | | Authors: | Polley, S, Passos, D, Huang, D, Biswas, T, Verma, I, Lyumkis, D, Ghosh, G. | | Deposit date: | 2015-10-20 | | Release date: | 2016-11-02 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (4.5 Å) | | Cite: | Structural Basis for the Activation of IKK1/ alpha.
Cell Rep, 17, 2016
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4Z74
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4Z70
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4Z73
 | | Crystal structure of inorganic pyrophosphatase from Mycobacterium tuberculosis in complex with a phosphate ion and an inorganic pyrophosphate | | Descriptor: | Inorganic pyrophosphatase, MANGANESE (II) ION, PHOSPHATE ION, ... | | Authors: | Pratt, A.C, Biswas, T, Tsodikov, O.V. | | Deposit date: | 2015-04-06 | | Release date: | 2015-08-26 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Structural and computational dissection of the catalytic mechanism of the inorganic pyrophosphatase from Mycobacterium tuberculosis.
J.Struct.Biol., 192, 2015
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4Z71
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4Z72
 | | Crystal structure of inorganic pyrophosphatase from Mycobacterium tuberculosis in complex with two phosphate ions | | Descriptor: | CALCIUM ION, Inorganic pyrophosphatase, PHOSPHATE ION | | Authors: | Pratt, A.C, Biswas, T, Barnard-Britson, S, Tsodikov, O.V. | | Deposit date: | 2015-04-06 | | Release date: | 2015-08-26 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.352 Å) | | Cite: | Structural and computational dissection of the catalytic mechanism of the inorganic pyrophosphatase from Mycobacterium tuberculosis.
J.Struct.Biol., 192, 2015
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4O8L
 | | Structure of sortase A from Streptococcus pneumoniae | | Descriptor: | Sortase | | Authors: | Misra, A, Biswas, T, Das, S, Marathe, U, Roy, R.P, Ramakumar, S. | | Deposit date: | 2013-12-28 | | Release date: | 2015-01-14 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structure of sortase A from Streptococcus pneumoniae
To be Published
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3PVV
 | | Structure of Mycobacterium tuberculosis DnaA-DBD in complex with box1 DNA | | Descriptor: | Chromosomal replication initiator protein dnaA, DNA (5'-D(*CP*GP*TP*TP*GP*TP*CP*CP*AP*CP*AP*AP*C)-3'), DNA (5'-D(*GP*TP*TP*GP*TP*GP*GP*AP*CP*AP*AP*CP*G)-3') | | Authors: | Tsodikov, O.V, Biswas, T. | | Deposit date: | 2010-12-07 | | Release date: | 2011-05-25 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural and Thermodynamic Signatures of DNA Recognition by Mycobacterium tuberculosis DnaA.
J.Mol.Biol., 410, 2011
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3PVP
 | | Structure of Mycobacterium tuberculosis DnaA-DBD in complex with box2 DNA | | Descriptor: | Chromosomal replication initiator protein dnaA, DNA (5'-D(*CP*GP*TP*TP*AP*TP*CP*CP*AP*CP*AP*AP*C)-3'), DNA (5'-D(*GP*TP*TP*GP*TP*GP*GP*AP*TP*AP*AP*CP*G)-3') | | Authors: | Tsodikov, O.V, Biswas, T. | | Deposit date: | 2010-12-07 | | Release date: | 2011-05-25 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structural and Thermodynamic Signatures of DNA Recognition by Mycobacterium tuberculosis DnaA.
J.Mol.Biol., 410, 2011
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5W33
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4O8T
 | | Structure of sortase A C207A mutant from Streptococcus pneumoniae | | Descriptor: | GLYCEROL, Sortase | | Authors: | Misra, A, Biswas, T, Das, S, Marathe, U, Roy, R.P, Ramakumar, S. | | Deposit date: | 2013-12-30 | | Release date: | 2015-01-14 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.48 Å) | | Cite: | Structure of sortase A C207A mutant from Streptococcus pneumoniae
To be Published
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2LCR
 | | NMR Structure of Alk1 extracellular domain | | Descriptor: | Activin receptor-like kinase 1 | | Authors: | Ilangovan, U. | | Deposit date: | 2011-05-06 | | Release date: | 2012-07-25 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | Structure of the Alk1 extracellular domain and characterization of its bone morphogenetic protein (BMP) binding properties.
Biochemistry, 51, 2012
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3N7Z
 | | Crystal structure of acetyltransferase from Bacillus anthracis | | Descriptor: | Acetyltransferase, GNAT family, SODIUM ION | | Authors: | Chang, C, Wu, R, Gornicki, P, Zhang, R, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | Deposit date: | 2010-05-27 | | Release date: | 2010-06-16 | | Last modified: | 2017-11-08 | | Method: | X-RAY DIFFRACTION (2.75 Å) | | Cite: | Biochemical and Structural Analysis of an Eis Family Aminoglycoside Acetyltransferase from Bacillus anthracis.
Biochemistry, 54, 2015
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5TQX
 | | CryoEM reconstruction of human IKK1, intermediate conformation 2 | | Descriptor: | Inhibitor of nuclear factor kappa-B kinase subunit alpha | | Authors: | Lyumkis, D, Ghosh, G, Polley, S, Biswath, T, Huang, D, Passos, D.O. | | Deposit date: | 2016-10-24 | | Release date: | 2016-11-09 | | Last modified: | 2024-03-13 | | Method: | ELECTRON MICROSCOPY (5.4 Å) | | Cite: | Structural Basis for the Activation of IKK1/ alpha.
Cell Rep, 17, 2016
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5TQW
 | | CryoEM reconstruction of human IKK1, open conformation 1 | | Descriptor: | Inhibitor of nuclear factor kappa-B kinase subunit alpha | | Authors: | Lyumkis, D, Ghosh, G, Polley, S, Biswath, T, Huang, D, Passos, D.O. | | Deposit date: | 2016-10-24 | | Release date: | 2016-11-09 | | Last modified: | 2024-03-13 | | Method: | ELECTRON MICROSCOPY (5.6 Å) | | Cite: | Structural Basis for the Activation of IKK1/ alpha.
Cell Rep, 17, 2016
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5TQY
 | | CryoEM reconstruction of human IKK1, closed conformation 3 | | Descriptor: | Inhibitor of nuclear factor kappa-B kinase subunit alpha | | Authors: | Lyumkis, D, Ghosh, G, Polley, S, Biswath, T, Huang, D, Passos, D.O. | | Deposit date: | 2016-10-24 | | Release date: | 2016-11-09 | | Last modified: | 2024-03-13 | | Method: | ELECTRON MICROSCOPY (5.2 Å) | | Cite: | Structural Basis for the Activation of IKK1/ alpha.
Cell Rep, 17, 2016
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5U01
 | | Cooperative DNA binding by two RelA dimers | | Descriptor: | DNA (27-MER), Transcription factor p65 | | Authors: | Ghosh, G, Huang, D. | | Deposit date: | 2016-11-22 | | Release date: | 2017-09-27 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | DNA-binding affinity and transcriptional activity of the RelA homodimer of nuclear factor kappa B are not correlated.
J. Biol. Chem., 292, 2017
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5W34
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5W35
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5W36
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5HZP
 | | Structure of human C4b-binding protein alpha chain CCP domains 1 and 2 in complex with the hypervariable region of group A Streptococcus M49 protein. | | Descriptor: | C4b-binding protein alpha chain, M protein, serotype 49, ... | | Authors: | Buffalo, C.Z, Bahn-Suh, A.J, Ghosh, P. | | Deposit date: | 2016-02-02 | | Release date: | 2016-07-20 | | Last modified: | 2019-12-11 | | Method: | X-RAY DIFFRACTION (2.74 Å) | | Cite: | Conserved patterns hidden within group A Streptococcus M protein hypervariability recognize human C4b-binding protein.
Nat Microbiol, 1, 2016
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5HYP
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5HYT
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5HYU
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