1XCG
| Crystal Structure of Human RhoA in complex with DH/PH fragment of PDZRHOGEF | Descriptor: | Rho guanine nucleotide exchange factor 11, Transforming protein RhoA | Authors: | Derewenda, U, Oleksy, A, Stevenson, A.S, Korczynska, J, Dauter, Z, Somlyo, A.P, Otlewski, J, Somlyo, A.V, Derewenda, Z.S. | Deposit date: | 2004-09-01 | Release date: | 2004-12-14 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The crystal structure of RhoA in complex with the DH/PH fragment of PDZRhoGEF, an activator of the Ca(2+) sensitization pathway in smooth muscle Structure, 12, 2004
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3FMS
| Crystal structure of TM0439, a GntR transcriptional regulator | Descriptor: | ACETATE ION, NICKEL (II) ION, Transcriptional regulator, ... | Authors: | Zheng, M, Cooper, D.R, Yu, M, Hung, L.-W, Derewenda, U, Derewenda, Z.S, Integrated Center for Structure and Function Innovation (ISFI) | Deposit date: | 2008-12-22 | Release date: | 2009-02-10 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure of Thermotoga maritima TM0439: implications for the mechanism of bacterial GntR transcription regulators with Zn2+-binding FCD domains. Acta Crystallogr.,Sect.D, 65, 2009
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3FHK
| Crystal structure of APC1446, B.subtilis YphP disulfide isomerase | Descriptor: | SULFATE ION, UPF0403 protein yphP | Authors: | Derewenda, U, Boczek, T, Cooper, D.R, Yu, M, Hung, L, Derewenda, Z.S, Integrated Center for Structure and Function Innovation (ISFI) | Deposit date: | 2008-12-09 | Release date: | 2009-09-01 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure and function of Bacillus subtilis YphP, a prokaryotic disulfide isomerase with a CXC catalytic motif . Biochemistry, 48, 2009
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1XAS
| CRYSTAL STRUCTURE, AT 2.6 ANGSTROMS RESOLUTION, OF THE STREPTOMYCES LIVIDANS XYLANASE A, A MEMBER OF THE F FAMILY OF BETA-1,4-D-GLYCANSES | Descriptor: | 1,4-BETA-D-XYLAN XYLANOHYDROLASE | Authors: | Derewenda, U, Derewenda, Z.S. | Deposit date: | 1994-05-31 | Release date: | 1995-05-31 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal structure, at 2.6-A resolution, of the Streptomyces lividans xylanase A, a member of the F family of beta-1,4-D-glycanases. J.Biol.Chem., 269, 1994
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1Y7M
| Crystal Structure of the B. subtilis YkuD protein at 2 A resolution | Descriptor: | CADMIUM ION, SULFATE ION, hypothetical protein BSU14040 | Authors: | Bielnicki, J.A, Devedjiev, Y, Derewenda, U, Dauter, Z, Joachimiak, A, Derewenda, Z.S, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2004-12-09 | Release date: | 2005-03-01 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | B. subtilis ykuD protein at 2.0 A resolution: insights into the structure and function of a novel, ubiquitous family of bacterial enzymes. Proteins, 62, 2006
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1TIC
| CONFORMATIONAL LABILITY OF LIPASES OBSERVED IN THE ABSENCE OF AN OIL-WATER INTERFACE: CRYSTALLOGRAPHIC STUDIES OF ENZYMES FROM THE FUNGI HUMICOLA LANUGINOSA AND RHIZOPUS DELEMAR | Descriptor: | LIPASE | Authors: | Derewenda, U, Swenson, L, Green, R, Joerger, R, Haas, M.J, Derewenda, Z.S. | Deposit date: | 1993-12-06 | Release date: | 1995-01-26 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Conformational lability of lipases observed in the absence of an oil-water interface: crystallographic studies of enzymes from the fungi Humicola lanuginosa and Rhizopus delemar. J.Lipid Res., 35, 1994
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1TIB
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3GOR
| Crystal structure of putative metal-dependent hydrolase APC36150 | Descriptor: | NICKEL (II) ION, Putative metal-dependent hydrolase | Authors: | Cooper, D.R, Grelewska, K, Derewenda, Z.S, Integrated Center for Structure and Function Innovation (ISFI) | Deposit date: | 2009-03-19 | Release date: | 2009-05-19 | Last modified: | 2017-11-01 | Method: | X-RAY DIFFRACTION (2.511 Å) | Cite: | The structure of DinB from Geobacillus stearothermophilus: a representative of a unique four-helix-bundle superfamily. Acta Crystallogr.,Sect.F, 66, 2010
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1FT0
| CRYSTAL STRUCTURE OF TRUNCATED HUMAN RHOGDI K113A MUTANT | Descriptor: | RHO GDP-DISSOCIATION INHIBITOR 1 | Authors: | Longenecker, K.L, Garrard, S.M, Sheffield, P.J, Derewenda, Z.S. | Deposit date: | 2000-09-11 | Release date: | 2001-05-02 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Protein crystallization by rational mutagenesis of surface residues: Lys to Ala mutations promote crystallization of RhoGDI. Acta Crystallogr.,Sect.D, 57, 2001
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1FSO
| CRYSTAL STRUCTURE OF TRUNCATED HUMAN RHOGDI QUADRUPLE MUTANT | Descriptor: | RHO GDP-DISSOCIATION INHIBITOR 1 | Authors: | Longenecker, K.L, Garrard, S.M, Sheffield, P.J, Derewenda, Z.S. | Deposit date: | 2000-09-11 | Release date: | 2001-05-02 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Protein crystallization by rational mutagenesis of surface residues: Lys to Ala mutations promote crystallization of RhoGDI. Acta Crystallogr.,Sect.D, 57, 2001
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1FTN
| CRYSTAL STRUCTURE OF THE HUMAN RHOA/GDP COMPLEX | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, TRANSFORMING PROTEIN RHOA (H12) | Authors: | Wei, Y, Zhang, Y, Derewenda, U, Liu, X, Minor, W, Nakamoto, R.K, Somlyo, A.V, Somlyo, A.P, Derewenda, Z.S. | Deposit date: | 1997-03-13 | Release date: | 1998-03-18 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structure of RhoA-GDP and its functional implications. Nat.Struct.Biol., 4, 1997
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1MJD
| Structure of N-terminal domain of human doublecortin | Descriptor: | DOUBLECORTIN | Authors: | Kim, M.H, Cierpicki, T, Derewenda, U, Krowarsch, D, Feng, Y, Devedjiev, Y, Dauter, Z, Walsh, C.A, Otlewski, J, Bushweller, J.H, Derewenda, Z.S. | Deposit date: | 2002-08-27 | Release date: | 2003-04-29 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | The DCX-domain Tandems of Doublecortin and Doublecortin-like Kinase Nat.Struct.Biol., 10, 2003
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5VIM
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5VKD
| Crystal structure of C-terminal domain of Ebola (Bundibugyo) nucleoprotein in complex with Fab fragment | Descriptor: | Fab Heavy Chain, Fab light chain, Nucleoprotein | Authors: | Radwanska, M.J, Derewenda, U, Kossiakoff, A, Derewenda, Z.S. | Deposit date: | 2017-04-21 | Release date: | 2018-04-25 | Last modified: | 2022-11-16 | Method: | X-RAY DIFFRACTION (1.749 Å) | Cite: | The structure of the C-terminal domain of the nucleoprotein from the Bundibugyo strain of the Ebola virus in complex with a pan-specific synthetic Fab. Acta Crystallogr D Struct Biol, 74, 2018
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5VI7
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5VZ1
| Crystal structure of the Apo Antibody fragment (Fab) raised against C-terminal domain of Ebola nucleoprotein (EBOV, TAFV, BDBV strains) | Descriptor: | Apo Antibody Fab Heavy Chain, Apo Antibody Fab Light Chain, ZINC ION | Authors: | Radwanska, M.J, Derewenda, U, Kossiakoff, A, Derewenda, Z.S. | Deposit date: | 2017-05-26 | Release date: | 2018-06-27 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.112 Å) | Cite: | Crystal structure of the Apo Antibody fragment (Fab) raised against C-terminal domain of Ebola nucleoprotein (EBOV, TAFV, BDBV strains) To Be Published
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5W2B
| Crystal structure of C-terminal domain of Ebola (Reston) nucleoprotein in complex with Fab fragment | Descriptor: | Fab Heavy Chain, Fab Light Chain, Nucleoprotein | Authors: | Radwanska, M.J, Derewenda, U, Kossiakoff, A.A, Derewenda, Z.S. | Deposit date: | 2017-06-06 | Release date: | 2018-06-13 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | The structure of the C-terminal domain of the nucleoprotein from the Bundibugyo strain of the Ebola virus in complex with a pan-specific synthetic Fab. Acta Crystallogr D Struct Biol, 74, 2018
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1H4R
| Crystal Structure of the FERM domain of Merlin, the Neurofibromatosis 2 Tumor Suppressor Protein. | Descriptor: | MERLIN, SULFATE ION | Authors: | Cooper, D.R, Kang, B.S, Sheffield, P, Devedjiev, Y, Derewenda, Z.S. | Deposit date: | 2001-05-14 | Release date: | 2002-01-16 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The Structure of the Ferm Domain of Merlin, the Neurofibromatosis Type 2 Gene Product. Acta Crystallogr.,Sect.D, 58, 2002
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3SXM
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3SXY
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3SXZ
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3SXK
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1N99
| CRYSTAL STRUCTURE OF THE PDZ TANDEM OF HUMAN SYNTENIN | Descriptor: | Syntenin 1 | Authors: | Kang, B.S, Cooper, D.R, Jelen, F, Devedjiev, Y, Derewenda, U, Dauter, Z, Otlewski, J, Derewenda, Z.S. | Deposit date: | 2002-11-22 | Release date: | 2003-04-15 | Last modified: | 2022-12-21 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | PDZ Tandem of Human Syntenin: Crystal Structure and Functional Properties Structure, 11, 2003
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1NTE
| CRYSTAL STRUCTURE ANALYSIS OF THE SECOND PDZ DOMAIN OF SYNTENIN | Descriptor: | OXYGEN ATOM, Syntenin 1 | Authors: | Kang, B.S, Cooper, D.R, Devedjiev, Y, Derewenda, U, Derewenda, Z.S. | Deposit date: | 2003-01-29 | Release date: | 2003-07-15 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.24 Å) | Cite: | Molecular roots of degenerate specificity in syntenin's PDZ2 domain: reassessment of the PDZ recognition paradigm. Structure, 11, 2003
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1OBX
| Crystal structure of the complex of PDZ2 of syntenin with an interleukin 5 receptor alpha peptide. | Descriptor: | COBALT (II) ION, INTERLEUKIN 5 RECEPTOR ALPHA, SULFATE ION, ... | Authors: | Kang, B.S, Cooper, D.R, Devedjiev, Y, Derewenda, U, Derewenda, Z.S. | Deposit date: | 2003-01-31 | Release date: | 2003-07-10 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Molecular Roots of Degenerate Specificity in Syntenin'S Pdz2 Domain: Reassessment of the Pdz Recognition Paradigm Structure, 11, 2003
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