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4I74
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BU of 4i74 by Molmil
Crystal structure of the Trypanosoma brucei Inosine-Adenosine-Guanosine nucleoside hydrolase in complex with compound UAMC-00312 and allosterically inhibited by a Ni2+ ion
Descriptor: (2R,3R,4S)-2-(hydroxymethyl)-1-[(4-hydroxythieno[3,2-d]pyrimidin-7-yl)methyl]pyrrolidine-3,4-diol, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, ...
Authors:Giannese, F, Degano, M.
Deposit date:2012-11-30
Release date:2013-08-07
Last modified:2013-12-18
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Structures of purine nucleosidase from Trypanosoma brucei bound to isozyme-specific trypanocidals and a novel metalorganic inhibitor
Acta Crystallogr.,Sect.D, 69, 2013
4I70
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BU of 4i70 by Molmil
Crystal structure of the Trypanosoma brucei Inosine-Adenosine-Guanosine nucleoside hydrolase
Descriptor: CALCIUM ION, Inosine-adenosine-guanosine-nucleoside hydrolase
Authors:Giannese, F, Degano, M.
Deposit date:2012-11-30
Release date:2013-08-07
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structures of purine nucleosidase from Trypanosoma brucei bound to isozyme-specific trypanocidals and a novel metalorganic inhibitor
Acta Crystallogr.,Sect.D, 69, 2013
3GSP
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BU of 3gsp by Molmil
RIBONUCLEASE T1 COMPLEXED WITH 2',3'-CGPS + 3'-GMP, 4 DAYS
Descriptor: CALCIUM ION, GUANOSINE-2',3'-CYCLOPHOSPHOROTHIOATE, GUANOSINE-3'-MONOPHOSPHATE, ...
Authors:Zegers, I, Wyns, L.
Deposit date:1997-12-02
Release date:1998-08-12
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Hydrolysis of a slow cyclic thiophosphate substrate of RNase T1 analyzed by time-resolved crystallography.
Nat.Struct.Biol., 5, 1998
1GSP
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BU of 1gsp by Molmil
RIBONUCLEASE T1 COMPLEXED WITH 2',3'-CGPS, 1 DAY
Descriptor: CALCIUM ION, GUANOSINE-2',3'-CYCLOPHOSPHOROTHIOATE, RIBONUCLEASE T1
Authors:Zegers, I, Wyns, L.
Deposit date:1997-11-28
Release date:1998-02-25
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Hydrolysis of a slow cyclic thiophosphate substrate of RNase T1 analyzed by time-resolved crystallography.
Nat.Struct.Biol., 5, 1998
6H02
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BU of 6h02 by Molmil
Crystal structure of human Mediator subunit MED23
Descriptor: LAMA nanobody NB106, Mediator of RNA polymerase II transcription subunit 23
Authors:Clantin, B, Monte, D, Villeret, V.
Deposit date:2018-07-06
Release date:2018-08-29
Last modified:2018-09-05
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of human Mediator subunit MED23.
Nat Commun, 9, 2018
6QX4
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BU of 6qx4 by Molmil
Structure of the Bacillus anthracis Sap S-layer assembly domain
Descriptor: Nanobody NbAF683, Nanobody NbAF694, S-layer protein sap
Authors:Remaut, H, Fioravanti, A.
Deposit date:2019-03-07
Release date:2019-07-31
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.27 Å)
Cite:Structure of S-layer protein Sap reveals a mechanism for therapeutic intervention in anthrax.
Nat Microbiol, 4, 2019
5N7O
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BU of 5n7o by Molmil
EthR2 in complex with SMARt-420 compound
Descriptor: 4,4,4-trifluoro-1-(3-phenyl-1-oxa-2,8-diazaspiro[4.5]dec-2-en-8-yl)butan-1-one, Probable transcriptional regulatory protein
Authors:Wohlkonig, A, Wintjens, R.
Deposit date:2017-02-21
Release date:2017-04-26
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural analysis of the interaction between spiroisoxazoline SMARt-420 and the Mycobacterium tuberculosis repressor EthR2.
Biochem. Biophys. Res. Commun., 487, 2017
8OPR
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BU of 8opr by Molmil
Structure of the EA1 surface layer of Bacillus anthracis
Descriptor: ACETATE ION, CALCIUM ION, Nanobody 632, ...
Authors:Sogues, A, Remaut, H.
Deposit date:2023-04-07
Release date:2023-11-08
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.811 Å)
Cite:Structure and function of the EA1 surface layer of Bacillus anthracis.
Nat Commun, 14, 2023
8OUI
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BU of 8oui by Molmil
Complex of ASCT2 with Suppressyn
Descriptor: ALANINE, Neutral amino acid transporter B(0), Suppressyn
Authors:Khare, S, Kumar, A, Reyes, N.
Deposit date:2023-04-23
Release date:2024-05-01
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.39 Å)
Cite:Receptor-recognition and antiviral mechanisms of retrovirus-derived human proteins.
Nat.Struct.Mol.Biol., 2024
8OUJ
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BU of 8ouj by Molmil
Heterotrimeric Complex of Human ASCT2 with Syncytin-1
Descriptor: ALANINE, Neutral amino acid transporter B(0), Syncytin-1
Authors:Khare, S, Reyes, N.
Deposit date:2023-04-23
Release date:2024-05-01
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Receptor-recognition and antiviral mechanisms of retrovirus-derived human proteins.
Nat.Struct.Mol.Biol., 2024
8OUH
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BU of 8ouh by Molmil
Complex of human ASCT2 with Syncytin-1
Descriptor: ALANINE, Neutral amino acid transporter B(0), Syncytin-1
Authors:Khare, S, Reyes, N.
Deposit date:2023-04-23
Release date:2024-05-01
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (2.62 Å)
Cite:Receptor-recognition and antiviral mechanisms of retrovirus-derived human proteins.
Nat.Struct.Mol.Biol., 2024
2LAL
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BU of 2lal by Molmil
CRYSTAL STRUCTURE DETERMINATION AND REFINEMENT AT 2.3 ANGSTROMS RESOLUTION OF THE LENTIL LECTIN
Descriptor: CALCIUM ION, LENTIL LECTIN (ALPHA CHAIN), LENTIL LECTIN (BETA CHAIN), ...
Authors:Loris, R, Steyaert, J, Maes, D, Lisgarten, J, Pickersgill, R, Wyns, L.
Deposit date:1993-06-10
Release date:1993-10-31
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural analysis of two crystal forms of lentil lectin at 1.8 A resolution.
Proteins, 20, 1994
5GSP
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BU of 5gsp by Molmil
RIBONUCLEASE T1/3'-GMP, 9 WEEKS
Descriptor: CALCIUM ION, GUANOSINE-3'-MONOPHOSPHATE, RIBONUCLEASE T1
Authors:Zegers, I, Wyns, L.
Deposit date:1997-12-09
Release date:1998-03-18
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Hydrolysis of a slow cyclic thiophosphate substrate of RNase T1 analyzed by time-resolved crystallography.
Nat.Struct.Biol., 5, 1998
5G5X
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BU of 5g5x by Molmil
CBS domain tandem of site-2 protease from Archaeoglobus fulgidus in complex with llama Nanobody - nucleotide-bound form
Descriptor: ADENOSINE MONOPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, NANOBODY, ...
Authors:Schacherl, M, Baumann, U.
Deposit date:2016-06-09
Release date:2017-05-24
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystallographic and biochemical characterization of the dimeric architecture of site-2 protease.
Biochim. Biophys. Acta, 1859, 2017
4DK3
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BU of 4dk3 by Molmil
Structure of Editosome protein
Descriptor: RNA-editing complex protein MP81, single domain antibody VHH
Authors:Park, Y.-J, Hol, W.
Deposit date:2012-02-03
Release date:2012-07-04
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.76 Å)
Cite:The structure of the C-terminal domain of the largest editosome interaction protein and its role in promoting RNA binding by RNA-editing ligase L2.
Nucleic Acids Res., 40, 2012
4DKA
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BU of 4dka by Molmil
Structure of Editosome protein
Descriptor: RNA-editing complex protein MP81, SODIUM ION, single domain antibody VHH
Authors:Park, Y.-J, Hol, W.
Deposit date:2012-02-03
Release date:2012-07-04
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:The structure of the C-terminal domain of the largest editosome interaction protein and its role in promoting RNA binding by RNA-editing ligase L2.
Nucleic Acids Res., 40, 2012
5IOF
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BU of 5iof by Molmil
Structure of the transmembrane domain of the transporter SLC26Dg
Descriptor: Sulphate transporter
Authors:Dutzler, R, Geertsma, E.R.G, Shaik, F.R.
Deposit date:2016-03-08
Release date:2016-03-16
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (4.2 Å)
Cite:Structure of a prokaryotic fumarate transporter reveals the architecture of the SLC26 family.
Nat. Struct. Mol. Biol., 22, 2015
4DK6
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BU of 4dk6 by Molmil
Structure of Editosome protein
Descriptor: RNA-editing complex protein MP81, single domain antibody VHH
Authors:Park, Y.-J, Hol, W.
Deposit date:2012-02-03
Release date:2012-07-04
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:The structure of the C-terminal domain of the largest editosome interaction protein and its role in promoting RNA binding by RNA-editing ligase L2.
Nucleic Acids Res., 40, 2012
5G5R
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BU of 5g5r by Molmil
CBS domain tandem of site-2 protease from Archaeoglobus fulgidus in complex with llama Nanobody - apo form
Descriptor: NANOBODY, SITE-2 PROTEASE, SULFATE ION
Authors:Schacherl, M, Baumann, U.
Deposit date:2016-06-02
Release date:2017-05-24
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystallographic and biochemical characterization of the dimeric architecture of site-2 protease.
Biochim. Biophys. Acta, 1859, 2017
4GGN
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BU of 4ggn by Molmil
Malaria invasion machinery protein complex
Descriptor: Myosin A tail domain interacting protein MTIP, Myosin-A
Authors:Khamrui, S, Turley, S, Bergman, L.W, Hol, W.G.J.
Deposit date:2012-08-06
Release date:2013-07-03
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:The structure of the D3 domain of Plasmodium falciparum myosin tail interacting protein MTIP in complex with a nanobody.
Mol.Biochem.Parasitol., 190, 2013
4GSP
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BU of 4gsp by Molmil
RIBONUCLEASE T1 COMPLEXED WITH 2',3'-CGPS + 3'-GMP, 7 DAYS
Descriptor: CALCIUM ION, GUANOSINE-2',3'-CYCLOPHOSPHOROTHIOATE, GUANOSINE-3'-MONOPHOSPHATE, ...
Authors:Zegers, I, Wyns, L.
Deposit date:1997-12-02
Release date:1998-08-12
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Hydrolysis of a slow cyclic thiophosphate substrate of RNase T1 analyzed by time-resolved crystallography.
Nat.Struct.Biol., 5, 1998
4FHB
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BU of 4fhb by Molmil
Enhancing DHFR catalysis by binding of an allosteric regulator nanobody (Nb179)
Descriptor: Dihydrofolate reductase, FOLIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Oyen, D.
Deposit date:2012-06-06
Release date:2013-04-24
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Mechanistic analysis of allosteric and non-allosteric effects arising from nanobody binding to two epitopes of the dihyrofolate reductase of Escherichia coli.
Biochim.Biophys.Acta, 1834, 2013
4M3J
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BU of 4m3j by Molmil
Structure of a single-domain camelid antibody fragment cAb-H7S specific of the BlaP beta-lactamase from Bacillus licheniformis
Descriptor: Camelid heavy-chain antibody variable fragment cAb-H7S, SULFATE ION
Authors:Pain, C, Kerff, F, Herman, R, Sauvage, E, Preumont, S, Charlier, P, Dumoulin, M.
Deposit date:2013-08-06
Release date:2014-08-06
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Probing the mechanism of aggregation of polyQ model proteins with camelid heavy-chain antibody fragments
To be Published
4M3K
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BU of 4m3k by Molmil
Structure of a single domain camelid antibody fragment cAb-H7S in complex with the BlaP beta-lactamase from Bacillus licheniformis
Descriptor: Beta-lactamase, CHLORIDE ION, Camelid heavy-chain antibody variable fragment cAb-H7S
Authors:Pain, C, Kerff, F, Herman, R, Sauvage, E, Preumont, S, Charlier, P, Dumoulin, M.
Deposit date:2013-08-06
Release date:2014-08-06
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Probing the mechanism of aggregation of polyQ model proteins with camelid heavy-chain antibody fragments
To be Published
4N1H
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BU of 4n1h by Molmil
Structure of a single-domain camelid antibody fragment cAb-F11N in complex with the BlaP beta-lactamase from Bacillus licheniformis
Descriptor: Beta-lactamase, Camelid heavy-chain antibody variable fragment cAb-F11N
Authors:Pain, C, Kerff, F, Herman, R, Sauvage, E, Preumont, S, Charlier, P, Dumoulin, M.
Deposit date:2013-10-04
Release date:2014-10-08
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:Probing the mechanism of aggregation of polyQ model proteins with camelid heavy-chain antibody fragments
To be Published

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