8EIC
Crystal structure of beta-catenin and the MDM2 p53-binding domain in complex with H330, a Helicon Polypeptide
Summary for 8EIC
| Entry DOI | 10.2210/pdb8eic/pdb |
| Descriptor | Catenin beta-1, E3 ubiquitin-protein ligase Mdm2, H330, ... (5 entities in total) |
| Functional Keywords | e3 ligase, complex, stapled peptide, ligase |
| Biological source | Homo sapiens (human) More |
| Total number of polymer chains | 3 |
| Total formula weight | 72090.43 |
| Authors | Li, K.,Travaline, T.L.,Swiecicki, J.-M.,Tokareva, O.S.,Thomson, T.M.,Verdine, G.L.,McGee, J.H. (deposition date: 2022-09-14, release date: 2023-10-25, Last modification date: 2023-11-15) |
| Primary citation | Tokareva, O.S.,Li, K.,Travaline, T.L.,Thomson, T.M.,Swiecicki, J.M.,Moussa, M.,Ramirez, J.D.,Litchman, S.,Verdine, G.L.,McGee, J.H. Recognition and reprogramming of E3 ubiquitin ligase surfaces by alpha-helical peptides. Nat Commun, 14:6992-6992, 2023 Cited by PubMed: 37914719DOI: 10.1038/s41467-023-42395-z PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.62 Å) |
Structure validation
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