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8VUW

ELIC5 with cysteamine in 2:1:1 POPC:POPE:POPG nanodisc in open conformation

Replaces:  8D68
Summary for 8VUW
Entry DOI10.2210/pdb8vuw/pdb
Related8D63 8D64 8D65 8D66 8D67
EMDB information27215 27216 27217 27218 27219 43542
DescriptorErwinia chrysanthemi ligand-gated ion channel, (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, 2-AMINO-ETHANETHIOL (3 entities in total)
Functional Keywordselic, ion channel, plgic, transport protein
Biological sourceDickeya chrysanthemi (Pectobacterium chrysanthemi, Erwinia chrysanthemi)
Total number of polymer chains5
Total formula weight189186.05
Authors
Petroff II, J.T.,Deng, Z.,Rau, M.J.,Fitzpatrick, J.A.J.,Yuan, P.,Cheng, W.W.L. (deposition date: 2024-01-29, release date: 2024-02-07)
Primary citationPetroff, J.T.,Dietzen, N.M.,Santiago-McRae, E.,Deng, B.,Washington, M.S.,Chen, L.J.,Trent Moreland, K.,Deng, Z.,Rau, M.,Fitzpatrick, J.A.J.,Yuan, P.,Joseph, T.T.,Henin, J.,Brannigan, G.,Cheng, W.W.L.
Open-channel structure of a pentameric ligand-gated ion channel reveals a mechanism of leaflet-specific phospholipid modulation.
Nat Commun, 13:7017-, 2022
Cited by
PubMed: 36385237
DOI: 10.1038/s41467-022-34813-5
PDB entries with the same primary citation
Experimental method
ELECTRON MICROSCOPY (3.19 Å)
Structure validation

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