7YMJ
Cryo-EM structure of alpha1AAR-Nb6 complex bound to tamsulosin
Summary for 7YMJ
Entry DOI | 10.2210/pdb7ymj/pdb |
Related | 7YM8 7YMH |
EMDB information | 33924 33928 33930 |
Descriptor | alpha1A-adrenergic receptor, Nb6, Tamsulosin (3 entities in total) |
Functional Keywords | gpcr, nanobody, antagonist, complex, membrane protein |
Biological source | Homo sapiens More |
Total number of polymer chains | 2 |
Total formula weight | 57728.28 |
Authors | Toyoda, Y.,Zhu, A.,Yan, C.,Kobilka, B.K.,Liu, X. (deposition date: 2022-07-28, release date: 2023-07-05) |
Primary citation | Toyoda, Y.,Zhu, A.,Kong, F.,Shan, S.,Zhao, J.,Wang, N.,Sun, X.,Zhang, L.,Yan, C.,Kobilka, B.K.,Liu, X. Structural basis of alpha 1A -adrenergic receptor activation and recognition by an extracellular nanobody. Nat Commun, 14:3655-3655, 2023 Cited by PubMed: 37339967DOI: 10.1038/s41467-023-39310-x PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.35 Å) |
Structure validation
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