5MYC

Crystal structure of human 14-3-3 sigma in complex with LRRK2 peptide pS910

Summary for 5MYC

Entry DOI	10.2210/pdb5myc/pdb
Descriptor	14-3-3 protein sigma, Leucine-rich repeat serine/threonine-protein kinase 2, CALCIUM ION, ... (6 entities in total)
Functional Keywords	14-3-3 lrrk2 phosphorylation ppi, transferase
Biological source	Homo sapiens (Human) More
Cellular location	Cytoplasm: P31947 Membrane; Peripheral membrane protein: Q5S007
Total number of polymer chains	2
Total formula weight	31140.33
Authors	Stevers, L.M.,de Vries, R.M.J.M.,Ottmann, C. (deposition date: 2017-01-26, release date: 2017-03-01, Last modification date: 2024-01-17)
Primary citation	Stevers, L.M.,de Vries, R.M.,Doveston, R.G.,Milroy, L.G.,Brunsveld, L.,Ottmann, C. Structural interface between LRRK2 and 14-3-3 protein. Biochem. J., 474:1273-1287, 2017 Cited by PubMed: 28202711 DOI: 10.1042/BCJ20161078 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.459 Å)

Structure validation