5K1X
Catalytic domain of polyspecific pyrrolysyl-tRNA synthetase mutant Y306A/N346A/C348A/Y384F in complex with AMPPNP
Summary for 5K1X
| Entry DOI | 10.2210/pdb5k1x/pdb |
| Related | 5K1P |
| Descriptor | Pyrrolysine--tRNA ligase, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, MAGNESIUM ION, ... (7 entities in total) |
| Functional Keywords | protein engineering, aminoacyl-trna synthetase, noncanonical amino acids, ligase |
| Biological source | Methanosarcina mazei |
| Total number of polymer chains | 1 |
| Total formula weight | 32419.76 |
| Authors | Weber, A. (deposition date: 2016-05-18, release date: 2016-10-19, Last modification date: 2024-03-06) |
| Primary citation | Lee, Y.J.,Schmidt, M.J.,Tharp, J.M.,Weber, A.,Koenig, A.L.,Zheng, H.,Gao, J.,Waters, M.L.,Summerer, D.,Liu, W.R. Genetically encoded fluorophenylalanines enable insights into the recognition of lysine trimethylation by an epigenetic reader. Chem.Commun.(Camb.), 52:12606-12609, 2016 Cited by PubMed: 27711380DOI: 10.1039/c6cc05959g PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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