5JTU

Crystal structure of GPb in complex with 8b

Summary for 5JTU

Entry DOI	10.2210/pdb5jtu/pdb
Descriptor	Glycogen phosphorylase, muscle form, PYRIDOXAL-5'-PHOSPHATE, (1S)-1,5-anhydro-1-[5-(naphthalen-2-yl)-1H-imidazol-2-yl]-D-glucitol, ... (5 entities in total)
Functional Keywords	alpha and beta protein transferase, transferase
Biological source	Oryctolagus cuniculus (Rabbit)
Total number of polymer chains	1
Total formula weight	98182.18
Authors	Kantsadi, A.L.,Stravodimos, G.A.,Chatzileontiadou, D.S.M.,Leonidas, D.D. (deposition date: 2016-05-09, release date: 2016-08-24, Last modification date: 2018-01-17)
Primary citation	Kantsadi, A.L.,Bokor, E.,Kun, S.,Stravodimos, G.A.,Chatzileontiadou, D.S.,Leonidas, D.D.,Juhasz-Toth, E.,Szakacs, A.,Batta, G.,Docsa, T.,Gergely, P.,Somsak, L. Synthetic, enzyme kinetic, and protein crystallographic studies of C-beta-d-glucopyranosyl pyrroles and imidazoles reveal and explain low nanomolar inhibition of human liver glycogen phosphorylase. Eur.J.Med.Chem., 123:737-745, 2016 Cited by PubMed: 27522507 DOI: 10.1016/j.ejmech.2016.06.049 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.85 Å)

Structure validation