5ITH
TIA-1 RRM2 recognition of target oligonucleotide
Summary for 5ITH
Entry DOI | 10.2210/pdb5ith/pdb |
Descriptor | Nucleolysin TIA-1 isoform p40, DNA (5'-D(*AP*CP*TP*CP*C*TP*TP*TP*TP*T)-3') (3 entities in total) |
Functional Keywords | rrm, rna/dna binding domain, poly u binding preference, aromatic base stacking interactions, dna binding protein-dna complex, rna binding protein-dna complex, rna binding protein/dna |
Biological source | Homo sapiens (Human) More |
Cellular location | Cytoplasmic granule : P31483 |
Total number of polymer chains | 2 |
Total formula weight | 13209.46 |
Authors | Waris, S.,Wilce, J.A.,Wilce, M.C. (deposition date: 2016-03-16, release date: 2017-02-22, Last modification date: 2023-09-27) |
Primary citation | Waris, S.,Garcia-Maurino, S.M.,Sivakumaran, A.,Beckham, S.A.,Loughlin, F.E.,Gorospe, M.,Diaz-Moreno, I.,Wilce, M.C.J.,Wilce, J.A. TIA-1 RRM23 binding and recognition of target oligonucleotides. Nucleic Acids Res., 45:4944-4957, 2017 Cited by PubMed: 28184449DOI: 10.1093/nar/gkx102 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.31 Å) |
Structure validation
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