5IFC

Crystal structure of polymerase acid protein (PA) from Influenza A virus, WILSON-SMITH/1933 (H1N1) bound to follow on fragment EBSI-4720 1-(4-bromophenyl)-1H-imidazole

Summary for 5IFC

• Entry DOI: 10.2210/pdb5ifc/pdb
• Related: 4iuj 5fic 5iex 5if2 5if5 5if7 5if8 5ifb
• Descriptor: Polymerase acidic protein, 1-(4-bromophenyl)-1H-imidazole, DIMETHYL SULFOXIDE, ... (4 entities in total)
• Functional Keywords: niaid, flu, structural genomics, fragment screening, std nmr, seattle structural genomics center for infectious disease, ssgcid, viral protein
• Biological source: Influenza A virus (strain A/Wilson-Smith/1933 H1N1)
• Cellular location: Host cytoplasm: P15659
• Total number of polymer chains: 1
• Total formula weight: 53397.93

Authors

Seattle Structural Genomics Center for Infectious Disease (SSGCID) (deposition date: 2016-02-25, release date: 2017-02-22, Last modification date: 2024-03-06)

• Primary citation: Pierce, P.,Muruthi, M.M.,Abendroth, J.,Moen, S.O.,Begley, D.W.,Davies, D.R.,Marathias, V.M.,Staker, B.L.,Myler, P.J.,Lorimer, D.D.,Edwards, T.E.; Fragment screening by STD NMR identifies novel site binders against influenza A virus polymerase PA; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.65 Å)