5HK5

Structure of the Grem2-GDF5 Inhibitory Complex

Summary for 5HK5

Entry DOI	10.2210/pdb5hk5/pdb
Descriptor	Gremlin-2, Growth/differentiation factor 5 (2 entities in total)
Functional Keywords	dan-family, bone morphogenetic proteins, cytokine
Biological source	Mus musculus (Mouse) More
Total number of polymer chains	8
Total formula weight	122424.48
Authors	Nolan, K.,Thompson, T.B.,Read, R.J. (deposition date: 2016-01-13, release date: 2016-08-24, Last modification date: 2023-09-27)
Primary citation	Nolan, K.,Kattamuri, C.,Rankin, S.A.,Read, R.J.,Zorn, A.M.,Thompson, T.B. Structure of Gremlin-2 in Complex with GDF5 Gives Insight into DAN-Family-Mediated BMP Antagonism. Cell Rep, 16:2077-2086, 2016 Cited by PubMed: 27524626 DOI: 10.1016/j.celrep.2016.07.046 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.9 Å)

Structure validation