5FYQ
Sirt2 in complex with a 13-mer trifluoroacetylated Ran peptide
Summary for 5FYQ
Entry DOI | 10.2210/pdb5fyq/pdb |
Descriptor | NAD-DEPENDENT PROTEIN DEACETYLASE SIRTUIN-2, RAN AA 31-43, SULFATE ION, ... (5 entities in total) |
Functional Keywords | hydrolase, sirtuin, kdac, lysine-deacetylase, lysine-acetylation, genetic-code expansion |
Biological source | HOMO SAPIENS (HUMAN) More |
Cellular location | Nucleus. Isoform 1: Cytoplasm . Isoform 2: Cytoplasm . Isoform 5: Cytoplasm : Q8IXJ6 Nucleus : P62826 |
Total number of polymer chains | 4 |
Total formula weight | 83835.91 |
Authors | Knyphausen, P.,de Boor, S.,Scislowski, L.,Extra, A.,Baldus, L.,Schacherl, M.,Baumann, U.,Neundorf, I.,Lammers, M. (deposition date: 2016-03-09, release date: 2016-05-25, Last modification date: 2024-01-10) |
Primary citation | Knyphausen, P.,De Boor, S.,Kuhlmann, N.,Scislowski, L.,Extra, A.,Baldus, L.,Schacherl, M.,Baumann, U.,Neundorf, I.,Lammers, M. Insights Into Lysine-Deacetylation of Natively Folded Substrate Proteins by Sirtuins. J.Biol.Chem., 291:14677-, 2016 Cited by PubMed: 27226597DOI: 10.1074/JBC.M116.726307 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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