5FS5
Breaking down the wall: mutation of the tyrosine gate of the universal Escherichia coli fimbrial adhesin FimH
Summary for 5FS5
Entry DOI | 10.2210/pdb5fs5/pdb |
Descriptor | FIMH, heptyl alpha-D-mannopyranoside, SODIUM ION, ... (4 entities in total) |
Functional Keywords | cell adhesion, bacterial adhesin, type 1 fimbriae, urinary tract infection, variable immunoglobulin fold |
Biological source | ESCHERICHIA COLI |
Total number of polymer chains | 1 |
Total formula weight | 17126.06 |
Authors | Bouckaert, J. (deposition date: 2015-12-30, release date: 2016-11-30, Last modification date: 2024-01-10) |
Primary citation | Rabbani, S.,Krammer, E.M.,Roos, G.,Zalewski, A.,Preston, R.,Eid, S.,Zihlmann, P.,Prevost, M.,Lensink, M.F.,Thompson, A.,Ernst, B.,Bouckaert, J. Mutation of Tyr137 of the universal Escherichia coli fimbrial adhesin FimH relaxes the tyrosine gate prior to mannose binding. IUCrJ, 4:7-23, 2017 Cited by PubMed: 28250938DOI: 10.1107/S2052252516016675 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.42 Å) |
Structure validation
Download full validation report