5F9B

X-ray crystal structure of PPARgamma in the complex with caulophyllogenin

Summary for 5F9B

Entry DOI	10.2210/pdb5f9b/pdb
Descriptor	Peroxisome proliferator-activated receptor gamma, Caulophyllogenin (3 entities in total)
Functional Keywords	nuclear receptor, transcription factor, diabetes, bundle of alpha-helices, transcription
Biological source	Homo sapiens (Human)
Cellular location	Nucleus: P37231
Total number of polymer chains	2
Total formula weight	65876.35
Authors	Pochetti, G.,Montanari, R.,Capelli, D. (deposition date: 2015-12-09, release date: 2016-06-29, Last modification date: 2024-01-10)
Primary citation	Montanari, R.,Capelli, D.,Tava, A.,Galli, A.,Laghezza, A.,Tortorella, P.,Loiodice, F.,Pochetti, G. Screening of saponins and sapogenins from Medicago species as potential PPAR gamma agonists and X-ray structure of the complex PPAR gamma /caulophyllogenin. Sci Rep, 6:27658-27658, 2016 Cited by PubMed: 27283034 DOI: 10.1038/srep27658 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.25 Å)

Structure validation