5EZY
Crystal structure of T2R-TTL-taccalonolide AJ complex
Summary for 5EZY
Entry DOI | 10.2210/pdb5ezy/pdb |
Descriptor | Tubulin alpha-1B chain, taccalonolide AJ, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ... (12 entities in total) |
Functional Keywords | tubulin, complex, inhibitor, structural protein |
Biological source | Rattus norvegicus (Rat) More |
Cellular location | Cytoplasm, cytoskeleton: Q2XVP4 Q6B856 Golgi apparatus : P63043 |
Total number of polymer chains | 6 |
Total formula weight | 265748.22 |
Authors | |
Primary citation | Wang, Y.,Yu, Y.,Li, G.B.,Li, S.A.,Wu, C.,Gigant, B.,Qin, W.,Chen, H.,Wu, Y.,Chen, Q.,Yang, J. Mechanism of microtubule stabilization by taccalonolide AJ Nat Commun, 8:15787-15787, 2017 Cited by PubMed: 28585532DOI: 10.1038/ncomms15787 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.05 Å) |
Structure validation
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