5EPH

Crystal structure of extended-spectrum beta-lactamase BEL-1 in complex with Imipenem

Replaces:  4MXB

Summary for 5EPH

• Entry DOI: 10.2210/pdb5eph/pdb
• Related: 5EOE 5EOO
• Descriptor: Beta-lactamase, CHLORIDE ION, Imipenem, ... (5 entities in total)
• Functional Keywords: hydrolase-antibiotic complex, extended-spectrum beta-lactamase, pseudomonas aeruginosa, hydrolase/antibiotic
• Biological source: Pseudomonas aeruginosa
• Total number of polymer chains: 4
• Total formula weight: 117187.66

Authors

Pozzi, C.,Benvenuti, M.,De Luca, F.,Docquier, J.D.,Mangani, S. (deposition date: 2015-11-11, release date: 2016-09-21, Last modification date: 2024-01-10)

• Primary citation: Pozzi, C.,De Luca, F.,Benvenuti, M.,Poirel, L.,Nordmann, P.,Rossolini, G.M.,Mangani, S.,Docquier, J.D.; Crystal Structure of the Pseudomonas aeruginosa BEL-1 Extended-Spectrum beta-Lactamase and Its Complexes with Moxalactam and Imipenem.; Antimicrob.Agents Chemother., 60:7189-7199, 2016; PubMed: 27671060; DOI: 10.1128/AAC.00936-16

Experimental method

X-RAY DIFFRACTION (1.79 Å)