5D96

Oxidoreductase Fragment of Mouse QSOX1 in Complex with a FAb Fragment from an Antibody Targeting Mouse and Human QSOX1

Summary for 5D96

• Entry DOI: 10.2210/pdb5d96/pdb
• Related: 4IJ3 5DI8
• Descriptor: Sulfhydryl oxidase 1, Light chain of Fab fragment from an antibody targeting mouse and human QSOX1, Heavy chain of Fab fragment from an antibody targeting mouse and human QSOX1, ... (4 entities in total)
• Functional Keywords: enzyme, inhibitor, antibody, dual-specificity, immune system
• Biological source: Mus musculus (Mouse); More
• Cellular location: Isoform 1: Golgi apparatus membrane ; Single-pass membrane protein . Isoform 2: Secreted. Isoform 3: Secreted. Isoform 4: Secreted: Q8BND5
• Total number of polymer chains: 6
• Total formula weight: 148018.05

Authors

Fass, D.,Grossman, I. (deposition date: 2015-08-18, release date: 2016-02-10, Last modification date: 2024-01-10)

• Primary citation: Grossman, I.,Ilani, T.,Fleishman, S.J.,Fass, D.; Overcoming a species-specificity barrier in development of an inhibitory antibody targeting a modulator of tumor stroma.; Protein Eng.Des.Sel., 29:135-147, 2016; PubMed: 26819240; DOI: 10.1093/protein/gzv067

Experimental method

X-RAY DIFFRACTION (2.3 Å)