5D7G

Structure of human ATG5 E122D-ATG16L1 complex at 3.0 Angstroms

Summary for 5D7G

• Entry DOI: 10.2210/pdb5d7g/pdb
• Descriptor: Autophagy protein 5, Autophagy-related protein 16-1 (3 entities in total)
• Functional Keywords: autophagy, apoptosis
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 8
• Total formula weight: 165489.22

Authors

Qiu, Y.,Schulman, B.A. (deposition date: 2015-08-13, release date: 2016-02-03, Last modification date: 2023-09-27)

• Primary citation: Kim, M.,Sandford, E.,Gatica, D.,Qiu, Y.,Liu, X.,Zheng, Y.,Schulman, B.A.,Xu, J.,Semple, I.,Ro, S.H.,Kim, B.,Mavioglu, R.N.,Tolun, A.,Jipa, A.,Takats, S.,Karpati, M.,Li, J.Z.,Yapici, Z.,Juhasz, G.,Lee, J.H.,Klionsky, D.J.,Burmeister, M.; Mutation in ATG5 reduces autophagy and leads to ataxia with developmental delay.; Elife, 5:-, 2016; PubMed: 26812546; DOI: 10.7554/eLife.12245

Experimental method

X-RAY DIFFRACTION (3 Å)