5D6Y
Crystal structure of double tudor domain of human lysine demethylase KDM4A complexed with histone H3K23me3
Summary for 5D6Y
Entry DOI | 10.2210/pdb5d6y/pdb |
Related | 5D6W 5D6X |
Descriptor | Lysine-specific demethylase 4A, peptide H3K23me3 (19-28) (3 entities in total) |
Functional Keywords | double tudor domain, reader domain, structural genomics, psi-2, protein structure initiative, enzyme discovery for natural product biosynthesis, natpro, oxidoreductase |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 10 |
Total formula weight | 86836.19 |
Authors | Wang, F.,Su, Z.,Miller, M.D.,Denu, J.M.,Phillips Jr., G.N.,Enzyme Discovery for Natural Product Biosynthesis (NatPro) (deposition date: 2015-08-13, release date: 2016-02-10, Last modification date: 2019-12-25) |
Primary citation | Su, Z.,Wang, F.,Lee, J.H.,Stephens, K.E.,Papazyan, R.,Voronina, E.,Krautkramer, K.A.,Raman, A.,Thorpe, J.J.,Boersma, M.D.,Kuznetsov, V.I.,Miller, M.D.,Taverna, S.D.,Phillips, G.N.,Denu, J.M. Reader domain specificity and lysine demethylase-4 family function. Nat Commun, 7:13387-13387, 2016 Cited by PubMed: 27841353DOI: 10.1038/ncomms13387 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.287 Å) |
Structure validation
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