5CGX
CRYSTAL STRUCTURE OF Fox-4 cephamycinase mutant Y150F complexed with cefoxitin
Summary for 5CGX
Entry DOI | 10.2210/pdb5cgx/pdb |
Related | 5CGS 5CGW 5CHJ 5CHM |
Descriptor | Beta-lactamase, (2R)-2-{(1S)-1-methoxy-2-oxo-1-[(thiophen-2-ylacetyl)amino]ethyl}-5-methylidene-5,6-dihydro-2H-1,3-thiazine-4-carboxylic acid, ZINC ION, ... (5 entities in total) |
Functional Keywords | beta-lactamase, hydrolase |
Biological source | Escherichia coli |
Total number of polymer chains | 1 |
Total formula weight | 39575.67 |
Authors | Malashkevich, V.N.,Toro, R.,Lefurgy, S.,Almo, S.C. (deposition date: 2015-07-09, release date: 2016-02-03, Last modification date: 2023-09-27) |
Primary citation | Lefurgy, S.T.,Malashkevich, V.N.,Aguilan, J.T.,Nieves, E.,Mundorff, E.C.,Biju, B.,Noel, M.A.,Toro, R.,Baiwir, D.,Papp-Wallace, K.M.,Almo, S.C.,Frere, J.M.,Bou, G.,Bonomo, R.A. FOX-4 cephamycinase: an analysis of structure and function. Antimicrob.Agents Chemother., 2015 Cited by PubMed: 26525784DOI: 10.1128/AAC.01887-15 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.21 Å) |
Structure validation
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