5AAO
Crystal structure of fluorogen-activating designed ankyrin repeat protein (DARPin) dimer in complex with malachite green
Summary for 5AAO
Entry DOI | 10.2210/pdb5aao/pdb |
Descriptor | FAD3210, 4-[[4-(dimethylamino)cyclohexa-2,5-dien-1-ylidene]-(4-methoxyphenyl)methyl]-N,N-dimethyl-aniline (3 entities in total) |
Functional Keywords | fluorescent protein, homodimer, designed ankyrin repeat protein (darpin), fluorogen-activation, malachite green |
Biological source | SYNTHETIC CONSTRUCT |
Total number of polymer chains | 12 |
Total formula weight | 224784.14 |
Authors | Batyuk, A.,Schuetz, M.,Kummer, L.,Wu, Y.,Mittl, P.,Plueckthun, A. (deposition date: 2015-07-27, release date: 2016-02-03, Last modification date: 2024-01-10) |
Primary citation | Schutz, M.,Batyuk, A.,Klenk, C.,Kummer, L.,de Picciotto, S.,Gulbakan, B.,Wu, Y.,Newby, G.A.,Zosel, F.,Schoppe, J.,Sedlak, E.,Mittl, P.R.,Zenobi, R.,Wittrup, K.D.,Pluckthun, A. Generation of Fluorogen-Activating Designed Ankyrin Repeat Proteins (FADAs) as Versatile Sensor Tools. J. Mol. Biol., 428:1272-1289, 2016 Cited by PubMed: 26812208DOI: 10.1016/j.jmb.2016.01.017 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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