5A6H
Synthesis, carbonic anhydrase inhibition and protein X-ray structure of the unusual natural product primary sulfonamide Psammaplin C
Summary for 5A6H
Entry DOI | 10.2210/pdb5a6h/pdb |
Descriptor | CARBONIC ANHYDRASE 2, ZINC ION, DIMETHYL SULFOXIDE, ... (5 entities in total) |
Functional Keywords | lyase, carbonic anhydrase inhibitor, natural product |
Biological source | HOMO SAPIENS (HUMAN) |
Total number of polymer chains | 1 |
Total formula weight | 30573.25 |
Authors | Mujumdar, P.,Supuran, C.T.,Peat, T.S.,Poulsen, S. (deposition date: 2015-06-26, release date: 2016-05-25, Last modification date: 2024-01-10) |
Primary citation | Mujumdar, P.,Teruya, K.,Tonissen, K.F.,Vullo, D.,Supuran, C.T.,Peat, T.S.,Poulsen, S. An Unusual Natural Product Primary Sulfonamide: Synthesis, Carbonic Anhydrase Inhibition and Protein X-Ray Structures of Psammaplin C. J.Med.Chem., 59:5462-, 2016 Cited by PubMed: 27172398DOI: 10.1021/ACS.JMEDCHEM.6B00443 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.57 Å) |
Structure validation
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