5LWE
Crystal structure of the human CC chemokine receptor type 9 (CCR9) in complex with vercirnon
Summary for 5LWE
Entry DOI | 10.2210/pdb5lwe/pdb |
Descriptor | C-C chemokine receptor type 9, Vercirnon, OLEIC ACID, ... (6 entities in total) |
Functional Keywords | membrane protein |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 85145.27 |
Authors | Oswald, C.,Rappas, M.,Kean, J.,Dore, A.S.,Errey, J.C.,Bennett, K.,Deflorian, F.,Christopher, J.A.,Jazayeri, A.,Mason, J.S.,Congreve, M.,Cooke, R.M.,Marshall, F.H. (deposition date: 2016-09-16, release date: 2016-12-07, Last modification date: 2024-01-17) |
Primary citation | Oswald, C.,Rappas, M.,Kean, J.,Dore, A.S.,Errey, J.C.,Bennett, K.,Deflorian, F.,Christopher, J.A.,Jazayeri, A.,Mason, J.S.,Congreve, M.,Cooke, R.M.,Marshall, F.H. Intracellular allosteric antagonism of the CCR9 receptor. Nature, 540:462-465, 2016 Cited by PubMed: 27926729DOI: 10.1038/nature20606 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
Download full validation report