5KUH

GluK2EM with LY466195

Summary for 5KUH

• Entry DOI: 10.2210/pdb5kuh/pdb
• Related: 5KUF
• EMDB information: 8289 8290
• Descriptor: Glutamate receptor ionotropic, kainate 2, (3S,4aR,6S,8aR)-6-{[(2S)-2-carboxy-4,4-difluoropyrrolidin-1-yl]methyl}decahydroisoquinoline-3-carboxylic acid (2 entities in total)
• Functional Keywords: gluk2em with ly466195, signaling protein
• Biological source: Rattus norvegicus (Rat); More
• Total number of polymer chains: 4
• Total formula weight: 343489.86

Authors

Meyerson, J.R.,Chittori, S.,Merk, A.,Rao, P.,Han, T.H.,Serpe, M.,Mayer, M.L.,Subramaniam, S. (deposition date: 2016-07-13, release date: 2016-09-07, Last modification date: 2024-03-06)

• Primary citation: Meyerson, J.R.,Chittori, S.,Merk, A.,Rao, P.,Han, T.H.,Serpe, M.,Mayer, M.L.,Subramaniam, S.; Structural basis of kainate subtype glutamate receptor desensitization.; Nature, 537:567-571, 2016; PubMed: 27580033; DOI: 10.1038/nature19352

Experimental method

ELECTRON MICROSCOPY (11.6 Å)