5F0P
Structure of retromer VPS26-VPS35 subunits bound to SNX3 and DMT1(L557M) (SeMet labeled)
Summary for 5F0P
Entry DOI | 10.2210/pdb5f0p/pdb |
Related | 2FAU 2R17 5F0J 5F0K 5F0L 5F0M |
Descriptor | Vacuolar protein sorting-associated protein 35, Vacuolar protein sorting-associated protein 26A, Sorting nexin-3, ... (9 entities in total) |
Functional Keywords | protein transport, retromer, sorting nexin |
Biological source | Homo sapiens (Human) More |
Cellular location | Cytoplasm: Q96QK1 O75436 Early endosome : O60493 Isoform 2: Cell membrane ; Multi- pass membrane protein . Endosome membrane ; Multi-pass membrane protein : P49281 |
Total number of polymer chains | 4 |
Total formula weight | 114930.16 |
Authors | Lucas, M.,Gershlick, D.,Vidaurrazaga, A.,Rojas, A.L.,Bonifacino, J.S.,Hierro, A. (deposition date: 2015-11-27, release date: 2016-12-07, Last modification date: 2024-01-10) |
Primary citation | Lucas, M.,Gershlick, D.C.,Vidaurrazaga, A.,Rojas, A.L.,Bonifacino, J.S.,Hierro, A. Structural Mechanism for Cargo Recognition by the Retromer Complex. Cell, 167:1623-1635.e14, 2016 Cited by PubMed: 27889239DOI: 10.1016/j.cell.2016.10.056 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.78 Å) |
Structure validation
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