5JZI

Crystal structure of 1406 TCR bound to HLA-A2 with HCV 1406-1415 antigen peptide

Replaces:  4ZEZ

Summary for 5JZI

• Entry DOI: 10.2210/pdb5jzi/pdb
• Descriptor: HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, KLV peptide, ... (6 entities in total)
• Functional Keywords: hcv1406 tcr, hla-a2, hcv ns3:1406-1415 peptide, decapeptide, protein binding, immune system complex, protein binding-immune system complex, protein binding/immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 10
• Total formula weight: 193365.12

Authors

Wang, Y.,Piepenbrink, K.H.,Baker, B.M. (deposition date: 2016-05-16, release date: 2017-05-31, Last modification date: 2023-09-27)

• Primary citation: Wang, Y.,Singh, N.K.,Spear, T.T.,Hellman, L.M.,Piepenbrink, K.H.,McMahan, R.H.,Rosen, H.R.,Vander Kooi, C.W.,Nishimura, M.I.,Baker, B.M.; How an alloreactive T-cell receptor achieves peptide and MHC specificity.; Proc. Natl. Acad. Sci. U.S.A., 114:E4792-E4801, 2017; PubMed: 28572406; DOI: 10.1073/pnas.1700459114

Experimental method

X-RAY DIFFRACTION (2.5 Å)