4Z1V
Structure of Factor Inhibiting HIF (FIH) in complex with Fe, NO, and NOG
Summary for 4Z1V
| Entry DOI | 10.2210/pdb4z1v/pdb |
| Related | 4Z2W |
| Descriptor | Hypoxia-inducible factor 1-alpha inhibitor, N-OXALYLGLYCINE, NITRIC OXIDE, ... (7 entities in total) |
| Functional Keywords | hypoxia inducible factor, factor inhibiting hif, hydroxylase, oxygen sensing, oxidoreductase |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 1 |
| Total formula weight | 41429.92 |
| Authors | Taabazuing, C.Y.,Garman, S.C.,Knapp, M.J. (deposition date: 2015-03-27, release date: 2016-01-13, Last modification date: 2023-09-27) |
| Primary citation | Taabazuing, C.Y.,Fermann, J.,Garman, S.,Knapp, M.J. Substrate Promotes Productive Gas Binding in the alpha-Ketoglutarate-Dependent Oxygenase FIH. Biochemistry, 55:277-286, 2016 Cited by PubMed: 26727884DOI: 10.1021/acs.biochem.5b01003 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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