4Z0J

F96S/S73A Double mutant of Plasmodium Falciparum Triosephosphate Isomerase

Summary for 4Z0J

• Entry DOI: 10.2210/pdb4z0j/pdb
• Related: 2VFD 2VFE 2VFF 2VFG 2VFH 4YWI 4YXG 4Z0S
• Descriptor: Triosephosphate isomerase, 1,2-ETHANEDIOL, SULFATE ION, ... (4 entities in total)
• Functional Keywords: tim barrels, beta-alpha barrels, isomerase, glycolysis
• Biological source: Plasmodium falciparum
• Total number of polymer chains: 2
• Total formula weight: 56876.29

Authors

Pareek, V.,Balaram, P.,Murthy, M.R.N. (deposition date: 2015-03-26, release date: 2016-02-03, Last modification date: 2023-11-08)

• Primary citation: Pareek, V.,Samanta, M.,Joshi, N.V.,Balaram, H.,Murthy, M.R.N.,Balaram, P.; Connecting Active-Site Loop Conformations and Catalysis in Triosephosphate Isomerase: Insights from a Rare Variation at Residue 96 in the Plasmodial Enzyme; Chembiochem, 17:620-629, 2016; PubMed: 26762569; DOI: 10.1002/cbic.201500532

Experimental method

X-RAY DIFFRACTION (2.07 Å)