4YOC
Crystal Structure of human DNMT1 and USP7/HAUSP complex
Summary for 4YOC
Entry DOI | 10.2210/pdb4yoc/pdb |
Descriptor | DNA (cytosine-5)-methyltransferase 1, Ubiquitin carboxyl-terminal hydrolase 7, ZINC ION, ... (4 entities in total) |
Functional Keywords | dna methylation, deubiquitination, dna methyltransferase, modification, transferase-hydrolase complex, transferase/hydrolase |
Biological source | Homo sapiens (Human) More |
Cellular location | Nucleus : P26358 Q93009 |
Total number of polymer chains | 2 |
Total formula weight | 178153.66 |
Authors | |
Primary citation | Cheng, J.,Yang, H.,Fang, J.,Ma, L.,Gong, R.,Wang, P.,Li, Z.,Xu, Y. Molecular mechanism for USP7-mediated DNMT1 stabilization by acetylation. Nat Commun, 6:7023-7023, 2015 Cited by PubMed: 25960197DOI: 10.1038/ncomms8023 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.916 Å) |
Structure validation
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