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4YOC

Crystal Structure of human DNMT1 and USP7/HAUSP complex

Summary for 4YOC
Entry DOI10.2210/pdb4yoc/pdb
DescriptorDNA (cytosine-5)-methyltransferase 1, Ubiquitin carboxyl-terminal hydrolase 7, ZINC ION, ... (4 entities in total)
Functional Keywordsdna methylation, deubiquitination, dna methyltransferase, modification, transferase-hydrolase complex, transferase/hydrolase
Biological sourceHomo sapiens (Human)
More
Cellular locationNucleus : P26358 Q93009
Total number of polymer chains2
Total formula weight178153.66
Authors
Cheng, J.,Yang, H.,Fang, J.,Gong, R.,Wang, P.,Li, Z.,Xu, Y. (deposition date: 2015-03-11, release date: 2015-05-27, Last modification date: 2023-11-08)
Primary citationCheng, J.,Yang, H.,Fang, J.,Ma, L.,Gong, R.,Wang, P.,Li, Z.,Xu, Y.
Molecular mechanism for USP7-mediated DNMT1 stabilization by acetylation.
Nat Commun, 6:7023-7023, 2015
Cited by
PubMed: 25960197
DOI: 10.1038/ncomms8023
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.916 Å)
Structure validation

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