4XW6

X-ray structure of PKAc with ADP, free phosphate ion, CP20, magnesium ions

Summary for 4XW6

• Entry DOI: 10.2210/pdb4xw6/pdb
• Related: 4XW4 4XW5
• Descriptor: cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor alpha, MAGNESIUM ION, ... (6 entities in total)
• Functional Keywords: protein kinase a, atp hydrolysis, catalytic subunit, atpase, transferase
• Biological source: Mus musculus (Mouse); More
• Cellular location: Cytoplasm . Isoform 2: Cell projection, cilium, flagellum : P05132
• Total number of polymer chains: 2
• Total formula weight: 44352.40

Authors

Gerlits, O.,Tian, J.,Das, A.,Taylor, S.,Langan, P.,Heller, T.W.,Kovalevsky, A. (deposition date: 2015-01-28, release date: 2015-05-06, Last modification date: 2023-09-27)

• Primary citation: Gerlits, O.,Tian, J.,Das, A.,Langan, P.,Heller, W.T.,Kovalevsky, A.; Phosphoryl Transfer Reaction Snapshots in Crystals: INSIGHTS INTO THE MECHANISM OF PROTEIN KINASE A CATALYTIC SUBUNIT.; J.Biol.Chem., 290:15538-15548, 2015; PubMed: 25925954; DOI: 10.1074/jbc.M115.643213

Experimental method

X-RAY DIFFRACTION (1.9 Å)