4X8P
Crystal structure of Ash2L SPRY domain in complex with RbBP5
Summary for 4X8P
Entry DOI | 10.2210/pdb4x8p/pdb |
Related | 4X8N |
Descriptor | Set1/Ash2 histone methyltransferase complex subunit ASH2,Set1/Ash2 histone methyltransferase complex subunit ASH2, Retinoblastoma-binding protein 5, GLYCEROL, ... (4 entities in total) |
Functional Keywords | histone, mll1, epigenetics, protein binding |
Biological source | Homo sapiens (Human) More |
Cellular location | Nucleus : Q9UBL3 Q15291 |
Total number of polymer chains | 2 |
Total formula weight | 22076.83 |
Authors | Zhang, P.,Chaturvedi, C.P.,Brunzelle, J.S.,Skiniotis, G.,Brand, M.,Shilatifard, A.,Couture, J.-F. (deposition date: 2014-12-10, release date: 2015-01-28, Last modification date: 2024-02-28) |
Primary citation | Zhang, P.,Chaturvedi, C.P.,Tremblay, V.,Cramet, M.,Brunzelle, J.S.,Skiniotis, G.,Brand, M.,Shilatifard, A.,Couture, J.F. A phosphorylation switch on RbBP5 regulates histone H3 Lys4 methylation. Genes Dev., 29:123-128, 2015 Cited by PubMed: 25593305DOI: 10.1101/gad.254870.114 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
Download full validation report