4OM3

Crystal structure of human TLE1 Q-domain residues 20-156

Summary for 4OM3

Entry DOI	10.2210/pdb4om3/pdb
Related	4om2
Descriptor	Transducin-like enhancer protein 1, GLYCEROL (2 entities in total)
Functional Keywords	tetramer, helix-turn-helix, wnt repressor, tcf/lef, transcription, dna binding
Biological source	Homo sapiens (human)
Cellular location	Nucleus: Q04724
Total number of polymer chains	4
Total formula weight	66792.25
Authors	Chodaparambil, J.V.,Weis, W.I. (deposition date: 2014-01-25, release date: 2014-04-09, Last modification date: 2024-02-28)
Primary citation	Chodaparambil, J.V.,Pate, K.T.,Hepler, M.R.,Tsai, B.P.,Muthurajan, U.M.,Luger, K.,Waterman, M.L.,Weis, W.I. Molecular functions of the TLE tetramerization domain in Wnt target gene repression. Embo J., 33:719-731, 2014 Cited by PubMed: 24596249 DOI: 10.1002/embj.201387188 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.855 Å)

Structure validation