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4JAZ

Crystal structure of the complex between PPARgamma LBD and trans-resveratrol

Summary for 4JAZ
Entry DOI10.2210/pdb4jaz/pdb
DescriptorPeroxisome proliferator-activated receptor gamma, RESVERATROL (3 entities in total)
Functional Keywordsbundle of alpha-helices, small four-strnded beta-sheet, activator, diabetes mellitus, disease mutation, dna-binding, nucleus, obesity, phosphorylation, receptor, transcription, transcription regulation
Biological sourceHomo sapiens (human)
Cellular locationNucleus: P37231
Total number of polymer chains2
Total formula weight65615.89
Authors
Pochetti, G.,Capelli, D.,Montanari, R.,Calleri, E.,Moaddel, R.,Temporini, C. (deposition date: 2013-02-19, release date: 2014-02-12, Last modification date: 2024-02-28)
Primary citationCalleri, E.,Pochetti, G.,Dossou, K.S.,Laghezza, A.,Montanari, R.,Capelli, D.,Prada, E.,Loiodice, F.,Massolini, G.,Bernier, M.,Moaddel, R.
Resveratrol and Its Metabolites Bind to PPARs.
Chembiochem, 15:1154-1160, 2014
Cited by
PubMed: 24796862
DOI: 10.1002/cbic.201300754
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.85 Å)
Structure validation

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