4J8S
Crystal structure of human CNOT1 MIF4G domain in complex with a TTP peptide
Summary for 4J8S
Entry DOI | 10.2210/pdb4j8s/pdb |
Descriptor | CCR4-NOT transcription complex subunit 1, Tristetraprolin (3 entities in total) |
Functional Keywords | mif4g, protein-protein interaction, ttp, cytosol, protein binding |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm, P-body : A5YKK6 Nucleus : P26651 |
Total number of polymer chains | 2 |
Total formula weight | 25791.35 |
Authors | Frank, F.,Fabian, M.R.,Rouya, C.,Siddiqui, N.,Lai, W.S.,Karetnikov, A.,Blackshear, P.J.,Sonenberg, N.,Nagar, B. (deposition date: 2013-02-14, release date: 2013-05-08, Last modification date: 2024-02-28) |
Primary citation | Fabian, M.R.,Frank, F.,Rouya, C.,Siddiqui, N.,Lai, W.S.,Karetnikov, A.,Blackshear, P.J.,Nagar, B.,Sonenberg, N. Structural basis for the recruitment of the human CCR4-NOT deadenylase complex by tristetraprolin. Nat.Struct.Mol.Biol., 20:735-739, 2013 Cited by PubMed: 23644599DOI: 10.1038/nsmb.2572 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.55 Å) |
Structure validation
Download full validation report