4FDD
Crystal structure of KAP beta2-PY-NLS
Summary for 4FDD
Entry DOI | 10.2210/pdb4fdd/pdb |
Related | 1qbk 2OT8 2QMR 2h4m |
Descriptor | Transportin-1, RNA-binding protein FUS (3 entities in total) |
Functional Keywords | heat repeats, karyopherin, nuclear import, protein transport, importin, transportin, transport protein |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm: Q92973 Nucleus : P35637 |
Total number of polymer chains | 2 |
Total formula weight | 99919.22 |
Authors | Zhang, Z.C.,Chook, Y.M. (deposition date: 2012-05-28, release date: 2012-07-18, Last modification date: 2024-02-28) |
Primary citation | Zhang, Z.C.,Chook, Y.M. Structural and energetic basis of ALS-causing mutations in the atypical proline-tyrosine nuclear localization signal of the Fused in Sarcoma protein (FUS). Proc.Natl.Acad.Sci.USA, 109:12017-12021, 2012 Cited by PubMed: 22778397DOI: 10.1073/pnas.1207247109 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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