4ERW
CDK2 in complex with staurosporine
Summary for 4ERW
Entry DOI | 10.2210/pdb4erw/pdb |
Related | 4EZ3 4EZ7 |
Descriptor | Cyclin-dependent kinase 2, STAUROSPORINE, 1,2-ETHANEDIOL, ... (4 entities in total) |
Functional Keywords | protein kinase, transferase-antibiotic complex, transferase/antibiotic |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm, cytoskeleton, centrosome: P24941 |
Total number of polymer chains | 1 |
Total formula weight | 36268.97 |
Authors | Alam, R.,Martin, M.P.,Zhu, J.-Y.,Schonbrunn, E. (deposition date: 2012-04-20, release date: 2012-08-22, Last modification date: 2023-12-06) |
Primary citation | Martin, M.P.,Alam, R.,Betzi, S.,Ingles, D.J.,Zhu, J.Y.,Schonbrunn, E. A Novel Approach to the Discovery of Small-Molecule Ligands of CDK2. Chembiochem, 13:2128-2136, 2012 Cited by PubMed: 22893598DOI: 10.1002/cbic.201200316 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
Download full validation report