4EAH

Crystal structure of the formin homology 2 domain of FMNL3 bound to actin

Summary for 4EAH

• Entry DOI: 10.2210/pdb4eah/pdb
• Descriptor: Actin, alpha skeletal muscle, Formin-like protein 3, ACETATE ION, ... (4 entities in total)
• Functional Keywords: atp binding, cytoskeleton, formin, fmnl3, actin, protein binding
• Biological source: Mus musculus (mouse); More
• Cellular location: Cytoplasm, cytoskeleton: P68135; Cytoplasm : Q6ZPF4
• Total number of polymer chains: 8
• Total formula weight: 355165.96

Authors

Thompson, M.E.,Heimsath, E.G.,Gauvin, T.J.,Higgs, H.N.,Kull, F.J. (deposition date: 2012-03-22, release date: 2012-12-12, Last modification date: 2024-02-28)

• Primary citation: Thompson, M.E.,Heimsath, E.G.,Gauvin, T.J.,Higgs, H.N.,Kull, F.J.; FMNL3 FH2-actin structure gives insight into formin-mediated actin nucleation and elongation.; Nat.Struct.Mol.Biol., 20:111-118, 2013; PubMed: 23222643; DOI: 10.1038/nsmb.2462

Experimental method

X-RAY DIFFRACTION (3.4 Å)