4CEM

Crystal structure of the first MIF4G domain of human nonsense mediated decay factor UPF2

Summary for 4CEM

• Entry DOI: 10.2210/pdb4cem/pdb
• Related: 4CEK
• Descriptor: REGULATOR OF NONSENSE TRANSCRIPTS 2 (2 entities in total)
• Functional Keywords: transcription
• Biological source: HOMO SAPIENS (HUMAN)
• Cellular location: Cytoplasm, perinuclear region: Q9HAU5
• Total number of polymer chains: 2
• Total formula weight: 85931.73

Authors

Clerici, M.,Deniaud, A.,Boehm, V.,Gehring, N.H.,Schaffitzel, C.,Cusack, S. (deposition date: 2013-11-11, release date: 2013-12-11, Last modification date: 2014-03-12)

• Primary citation: Clerici, M.,Deniaud, A.,Boehm, V.,Gehring, N.H.,Schaffitzel, C.,Cusack, S.; Structural and Functional Analysis of the Three Mif4G Domains of Nonsense-Mediated Decay Factor Upf2.; Nucleic Acids Res., 42:2673-, 2014; PubMed: 24271394; DOI: 10.1093/NAR/GKT1197

Experimental method

X-RAY DIFFRACTION (2.6 Å)