4YVA
Cathepsin K co-crystallized with actinomycetes extract
Summary for 4YVA
Entry DOI | 10.2210/pdb4yva/pdb |
Related | 4YV8 |
Descriptor | Cathepsin K, SULFATE ION (3 entities in total) |
Functional Keywords | cathepsin k, actinomycetes, hydrolase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 23619.54 |
Authors | Aguda, A.H.,Nguyen, N.T.,Bromme, D.,Brayer, G.D. (deposition date: 2015-03-19, release date: 2016-05-04, Last modification date: 2023-09-27) |
Primary citation | Aguda, A.H.,Lavallee, V.,Cheng, P.,Bott, T.M.,Meimetis, L.G.,Law, S.,Nguyen, N.T.,Williams, D.E.,Kaleta, J.,Villanueva, I.,Davies, J.,Andersen, R.J.,Brayer, G.D.,Bromme, D. Affinity Crystallography: A New Approach to Extracting High-Affinity Enzyme Inhibitors from Natural Extracts. J.Nat.Prod., 79:1962-1970, 2016 Cited by PubMed: 27498895DOI: 10.1021/acs.jnatprod.6b00215 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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